After we could demonstrate amyloid deposits both histochemically and ultrastructurally in the papillary body of typical skin lesions in 1 patient with ‘papillomatose papuleuse confluente et réticulée’ Gougerot-Carteaud (PCR), 2 other patients of our clinic already known to suffer from PCR were reinvestigated. Here, too, a similar amyloid storage was noted. In this paper, possible hypotheses concerning the etiopathology of these new results are proposed and the nosological significance of our findings is discussed, i.e. the PCR might lose its identification as a distinct pathological entity by the fact that 3 cases with the clinical picture of PCR can be subsumed under the nosological entity of primary localized skin amyloidoses.