Libidibia ferrea loaded in bacterial nanocellulose: evaluation of antimicrobial activity and wound care

Jozala, Ângela Faustino; Santos, Júlia Rodrigues dos; Santos, Gabriela R. dos; Viroel, Fabia Judice Marques; Pickler, Thaisa B.; Santos, Carolina Alves dos; Rebelo, Márcia A.; Chaud, Marco V.; Hataka, Alessandre; Grotto, Denise; Gerenutti, Marli; Nesiyama, Thaís Naomi Gonçalves

doi:10.34117/bjdv6n2-066

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“…The bark hydroalcoholic extract presented an antimicrobial potential with species from the Staphylococcus spp., obtaining inhibition halo sizes of 61.1%, 27.78%, and 5.56% for the crude extract at the 70% and 50% concentrations, respectively [ 70 ]. The aforementioned extract also presented an antimicrobial activity against S. aureus ATCC 10390, P. aeruginosa ATCC 9721, and E. coli ATCC 25,922 strains with MIC values of 0.39, 0.79, and 0.19 mg·mL −1 , respectively [ 67 ].…”

Section: Resultsmentioning

confidence: 99%

“…Diabetic and non-diabetic Wistar rats with lesions induced by thermal contact were treated with the C. ferrea bark hydroalcoholic extract incorporated with bacterial nanocellulose membranes, where the non-diabetic rat group exhibited epithelialization after 14 days of treatment, while the remaining animals presented epithelialization after 21 days of treatment [ 67 ].…”

Section: Resultsmentioning

confidence: 99%

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Caesalpinia ferrea C. Mart. (Fabaceae) Phytochemistry, Ethnobotany, and Bioactivities: A Review

et al. 2020

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Caesalpinia ferrea C. Mart., popularly known as “Jucá” or “Pau-ferro”, belongs to the Fabaceae family, and is classified as a native and endemic species in Brazil. Numerous studies that portray its ethnobotany, chemical composition, and biological activities exist in the literature. The present study aimed to systematically review publications addressing the botanical aspects, uses in popular medicine, phytochemical composition, and bioactivities of C. ferrea. The searches focused on publications from 2015 to March 2020 using the Scopus, Periódicos Capes, PubMed, Google Scholar, and ScienceDirect databases. The leaves, fruits, seeds, and bark from C. ferrea are used in popular medicine to treat disorders affecting several systems, including the circulatory, immune, cardiovascular, digestive, respiratory, genitourinary, musculoskeletal, and conjunctive systems. The most commonly found chemical classes in phytochemical studies are flavonoids, polyphenols, terpenoids, tannins, saponins, steroids, and other phenolic compounds. The biological properties of the extracts and isolated compounds of C. ferrea most cited in the literature were antibacterial, antifungal, antioxidant, antiproliferative, anti-inflammatory, and healing potential. However, further studies are still needed to clarify a link between its traditional uses, the active compounds, and the reported pharmacological activities, as well as detailed research to determine the toxicological profile of C. ferrea.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%