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“…While the apparent high level of fluoroquinolone susceptibility in S. pneumoniae has led some to express optimism regarding the role of fluoroquinolones in antipneumococcal therapy (32), concerns about future reductions in susceptibility continue to be expressed (33). Furthermore, although the overall fluoroquinolone susceptibility of S. pneumoniae remains high, investigators in certain geographic areas have reported alarming increases in fluoroquinolone resistance.…”
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“…While the apparent high level of fluoroquinolone susceptibility in S. pneumoniae has led some to express optimism regarding the role of fluoroquinolones in antipneumococcal therapy (32), concerns about future reductions in susceptibility continue to be expressed (33). Furthermore, although the overall fluoroquinolone susceptibility of S. pneumoniae remains high, investigators in certain geographic areas have reported alarming increases in fluoroquinolone resistance.…”
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