Leukocyte/platelet hybrid membrane-camouflaged dendritic large pore mesoporous silica nanoparticles co-loaded with photo/chemotherapeutic agents for triple negative breast cancer combination treatment

Zhang, Tao; Liu, Hui; Li, Ling; Guo, Zhaoyang; Song, Jia; Yang, Xiaoying; Wan, Guoyun; Li, Rongshan; Wang, Yinsong

doi:10.1016/j.bioactmat.2021.04.004

Cited by 66 publications

(50 citation statements)

References 34 publications

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“…The cells in the treatment group of LPHM@DDI NPs with laser irradiation exhibited the highest apoptosis rate, further verifying the synergistic anti-TNBC effect of photothermal therapy (PTT)/photodynamic therapy (PDT) and chemotherapy in vitro and also notably suppressed tumor growth and recurrence in TNBC mice through tumor ablation and antiangiogenesis. 142 Chen et al reported dual redox and antibody-responsive drug delivery system based on MSNs. In this study, anti-carbonic anhydrase IX antibody (A-CAIX Ab) was bonded on the MSN surface by disulfide linkages.…”

Section: Last Decade’s Advances On Novel Dual/multi-responsive Drug D...mentioning

confidence: 99%

How Advancing are Mesoporous Silica Nanoparticles? A Comprehensive Review of the Literature

Porrang¹,

Davaran²,

Rahemi³

et al. 2022

IJN

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The application of mesoporous silica nanoparticles (MSNs) is ubiquitous in various sciences. MSNs possess unique features, including the diversity in manufacturing by different synthesis methods and from different sources, structure controllability, pore design capabilities, pore size tunability, nanoparticle size distribution adjustment, and the ability to create diverse functional groups on their surface. These characteristics have led to various types of MSNs as a unique system for drug delivery. In this review, first, the synthesis of MSNs by different methods via using different sources were studied. Then, the parameters affecting their physicochemical properties and functionalization have been discussed. Finally, the last decade’s novel strategies, including surface functionalization, drug delivery, and cancer treatment, based on the MSNs in drug delivery and cancer therapy have been addressed.

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Section: Last Decade’s Advances On Novel Dual/multi-responsive Drug D...mentioning

confidence: 99%

How Advancing are Mesoporous Silica Nanoparticles? A Comprehensive Review of the Literature

Porrang¹,

Davaran²,

Rahemi³

et al. 2022

IJN

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“…164 In terms of the whole camouflage process, exosomes are first treated with a hypotonic solution to remove the cargo from the lumen and extract the exosomal membrane, after which the mixture of nanoparticles and extracted cell membrane is sonicated or repeatedly squeezed to complete the process. 165,166 Several studies have shown that cell membranes from red blood cells, tumour cells, platelets or white blood cells (WBCs) can be used to encapsulate nanoparticles for breast cancer treatment, and that different combinations can be used with varying degrees of efficacy 78,[167][168][169][170][171] (Table 6).…”

Section: Bionic Therapy Based On Membrane Camouflage Technologymentioning

confidence: 99%

Exosome-based delivery nanoplatforms: next-generation theranostic platforms for breast cancer

Zheng

Weng

et al. 2022

Biomater. Sci.

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“…Leukocyte membrane-encapsulated nanoparticles have been demonstrated to be ideal particles that are suitable for phototherapy, and they could improve the biocompatibility and targeting capability of PTA or photosensitizers by systemic administration . Stem cells and several cancer cell membrane-coated nanocarriers have been constructed for phototherapy to dramatically enhance antitumor efficacy due to their homotypic targeting behaviors and remarkable accumulation at tumor sites. − The proper combination of the above two cell membranes can optimize the therapeutic effect of phototherapy …”

Section: Biomedical Applications Of Hm@bnpsmentioning

confidence: 99%

Hybrid Membrane-Coated Biomimetic Nanoparticles (HM@BNPs): A Multifunctional Nanomaterial for Biomedical Applications

Zhao

Jiang

et al. 2021

Biomacromolecules

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The application of nanoparticles in the diagnosis and treatment of diseases has undergone different developmental stages, but phagocytosis and nonspecific distribution have been the main factors restricting the transformation of nanobased drugs into clinical practice. In the past decade, the design of membrane-coated nanoparticles has gained increasing attention. It is hoped that the combination of the cell membrane's natural biological properties and the functional integration of synthetic nanoparticle systems can compensate for the shortage of traditional nanoparticles. The membrane coating gives the nanoparticles unique biological functions such as immune evasion and targeting capability. However, when the encapsulation of monotypic membranes does not meet the diverse demands of biomedicine, the combination of different cell membranes may offer more possibilities. In this review, the composition, preparation, and advantages of biomimetic nanoparticles coated with hybrid cell membranes are summarized, and the applications of hybrid membrane-coated biomimetic nanoparticles (HM@BNPs) in drug delivery, phototherapy, liquid biopsy, tumor vaccines, immune therapy, and detoxification are reviewed. Finally, the current challenges and opportunities with regard to HM@BNPs are discussed.

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Leukocyte/platelet hybrid membrane-camouflaged dendritic large pore mesoporous silica nanoparticles co-loaded with photo/chemotherapeutic agents for triple negative breast cancer combination treatment

Cited by 66 publications

References 34 publications

How Advancing are Mesoporous Silica Nanoparticles? A Comprehensive Review of the Literature

How Advancing are Mesoporous Silica Nanoparticles? A Comprehensive Review of the Literature

Exosome-based delivery nanoplatforms: next-generation theranostic platforms for breast cancer

Hybrid Membrane-Coated Biomimetic Nanoparticles (HM@BNPs): A Multifunctional Nanomaterial for Biomedical Applications

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