Leucoencefalopatia multifocale progressiva

Editorial: Immune Control of JC Virus Infection and Immune Failure during Progressive Multifocal Leukoencephalopathy

“…PML, once a medical curiosity, entered the hall of infamy first during the AIDS pandemic and then as a major adverse effect of potent new immunosuppressive biologics such as natalizumab. AIDS, hematological malignancies, and natalizumab now account for more than 90% of all PML cases ( 3 ).…”