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“…Several authors have commented on the imperfect correlation be tween the existence of acute renal failure in man and the histologic appearance of the kidney [5,6,21]. Histologic evidence of injury may be minimal in patients whose renal function impairment is severe.…”
Section: Discussionmentioning
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“…Several authors have commented on the imperfect correlation be tween the existence of acute renal failure in man and the histologic appearance of the kidney [5,6,21]. Histologic evidence of injury may be minimal in patients whose renal function impairment is severe.…”
Section: Discussionmentioning
“…In a controlled autopsy study, Finckh, Jeremey, and Whyte found instances of acute renal failure associated with minimal abnormalities of the tubules, although kidneys of some patients who did not have renal failure had relatively severe tubular lesions. Nor is there any necessary correlation between the degree of functional impairment and the histologic appearance of the kidney in renal biopsy specimens taken 2 to 66 days after the onset of anuria (19). The concept of a tubular basis for oliguria receives support from a widely quoted micropuncture study of Richards (20).…”
Section: Discussionmentioning
“…We have used the term "acute renal failure" to describe the similar consequences of glycerol injection in the rabbit. We do not imply that acute tubular necrosis is the pathological counterpart of ARF since either condition frequently occurs without the other (19)(20)(21).…”
Section: Terminologymentioning