Lesion Localization in Aphasia With Cranial Computed Tomography and the Boston Diagnostic Aphasia Exam

Naeser, Margaret A.; Hayward, Robert W.; Seigel, Robert

doi:10.1097/00004728-197904000-00035

Cited by 34 publications

(43 citation statements)

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“…They are also in accordance with the data from the literature concerning the correlations between the severity of the language disorder and the volume of the in farct [14,15,18,23]. Nevertheless, a closer analysis of our material (the distinction be tween the patients with a superficial and a deep lesion) and of our data (separate assess ment of comprehension and expression) brought to light new information.…”

Section: Discussionsupporting

confidence: 91%

Prognostic Value of Computed Tomography in Aphasic Stroke Patients

Demeurisse¹,

Capon²,

Verhas

1985

Eur Neurol

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In order to evaluate the prognostic value of CT scan in aphasic stroke patients, a prospective study was performed during the first 3 months of the disease. The severity of the language disorders was assessed by means of a quantitative method. In cortico-subcortical lesions, the verbal expression recovery rate and the final verbal expression and comprehension status depended on the infarct size. No relation was observed between the latter and the verbal comprehension recovery rate. In deep-seated lesions, computed tomography provided no information concerning the prognosis.

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Section: Discussionsupporting

confidence: 91%

Prognostic Value of Computed Tomography in Aphasic Stroke Patients

Demeurisse¹,

Capon²,

Verhas

1985

Eur Neurol

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“…The cognitive battery included the Wechsler Digit Span Forward (revised to assess attention) [13] , Boston Diagnostic Aphasia Examination Repetition and Comprehension (combined, possible range 0-12) [14] , Immediate Recall of a 10-word list, Delayed Word Recall (11-min average delay), the 1-min Animal Naming test and Trailmaking tests A and B. We present results for each test separately and for a combined summary cognitive measure.…”

Section: Methodsmentioning

confidence: 99%

Social Ties and Cognitive Recovery after Stroke: Does Social Integration Promote Cognitive Resilience?

et al. 2008

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Background/Aims: Little is known about the possible effects of social resources on stroke survivors’ level and change in cognitive outcomes. Understanding this association may help us identify strategies to improve stroke recovery and help elucidate the etiology of dementia. Methods: We examined the relationship of social ties and social support to cognitive function and cognitive change 6 months after stroke. Participants in the Families in Recovery from Stroke Trial (FIRST) (n = 272) were interviewed approximately 17 days (baseline) and 6 months (follow-up) after stroke. Cognition was assessed with the Mini Mental State Examination (MMSE) and a summary battery of 7 neuropsychological tests. Median-based regression was used to model cognitive outcomes by level of baseline intimate, personal and organizational social ties and received emotional and instrumental support. Results: Baseline social ties and emotional sup- port independently predicted 6-month Cognitive Summary Scores. Emotional support also predicted greater improvements in Cognitive Summary Scores from baseline to the 6-month follow-up. No other social exposures predicted improvements in the MMSE or the Cognitive Summary. Conclusions: Our results suggest that emotional support may promote cognitive resilience while social ties provide cognitive reserve that protects against impaired cognition after stroke. Social ties did not predict cognitive recovery however, so reverse causation cannot be ruled out.

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“…In the past, standard templates were most often sets of two-dimensional brain images acquired in single orientation. Lesions were transferred onto these templates, and the results were described qualitatively or quantitatively according to regions of interest [e.g., see Damasio and Damasio, 1980;Kunesch et al, 1995;Naeser and Hayward, 1978;Woods et al, 1993, and many others].…”

Section: Lesion Warpingmentioning

confidence: 99%

Lesion segmentation and manual warping to a reference brain: Intra- and interobserver reliability

2000

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The study of subjects with acquired brain damage has been an invaluable tool for exploring human brain function, and the description of lesion locations within and across subjects is an important component of this method. Such descriptions usually involve the separation of lesioned from nonlesioned tissue (lesion segmentation) and the description of the lesion location in terms of a standard anatomical reference space (lesion warping). The objectives of this study were to determine the sources and magnitude of variability involved in lesion segmentation and warping using the MAP-3 approach. Each of two observers segmented the lesion volume in ten brain-damaged subjects twice, so as to permit pairwise comparisons of both intra- and interobserver agreement. The segmented volumes were then warped to a reference brain using both a manual (MAP-3) and an automated (AIR-3) technique. Observer agreement between segmented and warped volumes was analyzed using four measures: volume size, distance between the volume surfaces, percentage of nonoverlapping voxels, and percentage of highly discrepant voxels. The techniques for segmentation and warping produced high agreement within and between observers. For example, in most instances, the warped volume surfaces created by different observers were separated by less than 3 mm. The performance of the automated warping technique compared favorably to the manual technique in most subjects, although important exceptions were found. Overall, these results establish benchmark parameters for expert and automated lesion transfer, and indicate that a high degree of confidence can be placed in the detailed anatomical interpretation of focal brain damage based upon the MAP-3 technique.

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Lesion Localization in Aphasia With Cranial Computed Tomography and the Boston Diagnostic Aphasia Exam

Cited by 34 publications

References 0 publications

Prognostic Value of Computed Tomography in Aphasic Stroke Patients

Prognostic Value of Computed Tomography in Aphasic Stroke Patients

Social Ties and Cognitive Recovery after Stroke: Does Social Integration Promote Cognitive Resilience?

Lesion segmentation and manual warping to a reference brain: Intra- and interobserver reliability

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