Lesão Renal Tubular Aguda Em Cães E Gatos: Fisiopatogenia E Diagnóstico Ultrassonográfico

Bragato, Nathália; Fíoravantí, Maria Clorínda Soares; Braga, Larissa Graciano; Reis, Danielly Cunha dos; Borges, Naída Cristina

doi:10.18677/enciclopedia_biosfera_2015_183

Cited by 3 publications

(3 citation statements)

References 17 publications

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“…Most patients had a preserved corticomedullary ratio. These results are in agreement with Bragato et al (2015), who mentioned that diffuse renal changes can be hard to diagnose via B-mode ultrasound. When present, common changes would be nephromegaly, increased or decreased echogenicity of the renal cortex, renal pelvis dilation, among others.…”

Section: Discussionsupporting

confidence: 92%

Ultrasonographic Assessment of Renal Perfusion in Bitches With Mammary Carcinoma Treated With Long-Term Carprofen

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Objective. The aim of this study was to evaluate renal hemodynamics, routine clinical and laboratory parameters used to estimate renal function, and clinical evolution during six months in bitches with mammary carcinomas that underwent mastectomy and were treated (TG) or not (CG) with carprofen for three months after surgery. Methods. Twenty-six bitches with mammary neoplasia were equally distributed into TG that received carprofen 4.4 mg/kg/day for 90 days and CG that did not receive anti-inflammatory medication. Renal artery Doppler flowmetry, contrast-enhanced ultrasound (CEUS) of renal parenchyma, haematological, biochemical and clinical analyses were obtained once a month. These data were compared between groups and moments via analysis of variance (ANOVA) in a completely randomized design with repeated measures (P<0.05). Results. On B-mode ultrasound, the area of the renal artery was greater (P=0.0003) in the TG. Regarding laboratory findings, haematocrit and haemoglobin were similar in both groups, showing a significant and gradual increase after three months of treatment; MCV, MHC, and MCHC were increased (P<0.05) and lymphocyte and band counts decreased (P<0.05) in the TG. Regarding biochemical tests, ALT was the only parameter with a significant difference, being higher (P=0.0272) in the treated group.Conclusion. It can be concluded that the use of carprofen for 90 days causes minimal changes in renal perfusion, erythrocyte parameters and ALT activity, and reduces the proportion of blood inflammatory cells. Therefore, use of this medication can be carried out safely in patients who require auxiliary cancer treatment.

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Section: Discussionsupporting

confidence: 92%

Ultrasonographic Assessment of Renal Perfusion in Bitches With Mammary Carcinoma Treated With Long-Term Carprofen

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et al. 2021

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“…Classifica-se a necrose tubular aguda como isquêmica e nefrotóxica, tendo como principal meio de diagnóstico o exame clínico, ultrassonografia e exames laboratoriais. Associando-se frequentemente a fatores extrínsecos tais como os agentes potencialmente nefrotóxicos, hipoperfusão ou hipovolemia; caracteriza-se por ser responsável por 33,2% de complicações renais graves (Bello et al, 2017;Bragato, Fioravanti, Braga, Reis & Borges, 2015).…”

Section: Discussionunclassified

Fatores de risco para Lesão Renal Aguda em Unidade de Terapia Intensiva

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et al. 2021

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Objetivo: avaliar as condições clínicas e intervenções terapêuticas que predispõem a ocorrência da IRA nos pacientes internados em UTI. Método: trata-se de uma Revisão Sistemática da Literatura nas seguintes fontes de dados: PUBMED, MEDLINE, LILACS, BDENF e SCIELO. As evidências dos estudos foram classificadas conforme (XX). Foram utilizados os seguintes descritores: “Hemodiálise” AND “Terapia intensiva”. Resultados: destaca-se que a IRA na UTI está relacionada à: fatores de risco associados à terapêutica (uso de DVA, VMI, antibioticoterapia, nefropatia medicamentosa e induzida pelo uso de contraste à base de iodo); comorbidades (DM, HAS, pulmonares, digestivas, hepáticas, neoplasias, anemia, obesidade e imunossupressão), agravos agudos (trauma, hemorragia, acidente ofídico, choque, infecção, sepse, eclâmpsia; complicações de doença cardiovascular, de doença neurológica aguda, necrose tubular aguda, síndrome hepatorenal e acidentes com animais peçonhentos), idade, distúrbios hidroeletrolíticos (hipercalcêmia, hipocalcêmia, hipernatremia e a hiponatremia), distúrbios do equilíbrio ácido básico, balanço hídrico acumulativo e necrose tubular aguda. Conclusão: constata-se que a IRA na UTI tem relaciona-se com a condição clínica do paciente e intervenções terapêuticas realizadas na UTI.

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“…These results are in agreement with previously published findings which stated that diffuse renal changes can be hard to diagnose via B-mode ultrasound. When present, common changes would be nephromegaly, increased or decreased echogenicity of the renal cortex, renal pelvis dilation, among others 7 .…”

Section: Discussionmentioning

confidence: 99%

Ultrasonographic assessment of renal perfusion in bitches with mammary carcinoma treated with long-term carprofen

Estrada

Firmo

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et al. 2021

Sci Rep

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The aim of this study was to evaluate renal hemodynamics, routine clinical and laboratory parameters used to estimate renal function, and clinical evolution during six months in bitches with mammary carcinomas that underwent mastectomy and were treated (TG) or not (CG) with carprofen for three months after surgery. Twenty-six bitches with mammary carcinoma were equally distributed into TG that received carprofen 4.4 mg/kg/day for 90 days and CG that did not receive anti-inflammatory medication. Renal artery Doppler flowmetry, contrast-enhanced ultrasound (CEUS) of renal parenchyma, haematological, biochemical and clinical analyses were obtained once a month. These data were compared between groups and time via analysis of variance (ANOVA) in a completely randomized design with repeated measures (P < 0.05). On B-mode ultrasound, the area of the renal artery was greater (P = 0.0003) in the TG. Regarding laboratory findings, haematocrit and haemoglobin were similar in both groups, showing a significant and gradual increase after three months of treatment; MCV, MHC, and MCHC were increased (P < 0.05) and lymphocyte and band counts decreased (P < 0.05) in the TG. Regarding biochemical tests, ALT was the only parameter with a significant difference, being higher (P = 0.0272) in the treated group. It can be concluded that the use of carprofen for 90 days causes minimal changes in renal perfusion, erythrocyte parameters and ALT activity, and reduces the proportion of blood inflammatory cells. Therefore, use of this medication can be carried out safely in patients who require auxiliary cancer treatment.

show abstract

Lesão Renal Tubular Aguda Em Cães E Gatos: Fisiopatogenia E Diagnóstico Ultrassonográfico

Cited by 3 publications

References 17 publications

Ultrasonographic Assessment of Renal Perfusion in Bitches With Mammary Carcinoma Treated With Long-Term Carprofen

Ultrasonographic Assessment of Renal Perfusion in Bitches With Mammary Carcinoma Treated With Long-Term Carprofen

Fatores de risco para Lesão Renal Aguda em Unidade de Terapia Intensiva

Ultrasonographic assessment of renal perfusion in bitches with mammary carcinoma treated with long-term carprofen

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