Weedon's Skin Pathology 2010
DOI: 10.1016/b978-0-7020-3485-5.00033-4
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Lentigines, nevi, and melanomas

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Cited by 32 publications
(33 citation statements)
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References 2,475 publications
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“…The thickness at the time of detection of tumors in hard to detect areas is generally larger that those in easy to see areas. it is therefore said that tumors localized in the extremities have better survival rates than those localized in the head-neck or body (6). The presence of CoE more commonly in tumors with a head-neck localization in this study can also indicate the possible use of CoE as an unfavorable prognostic indicator.…”
Section: Discussionmentioning
confidence: 58%
“…The thickness at the time of detection of tumors in hard to detect areas is generally larger that those in easy to see areas. it is therefore said that tumors localized in the extremities have better survival rates than those localized in the head-neck or body (6). The presence of CoE more commonly in tumors with a head-neck localization in this study can also indicate the possible use of CoE as an unfavorable prognostic indicator.…”
Section: Discussionmentioning
confidence: 58%
“…Although some morphologically similar lesions lack S100 expression (such as cellular neurothekeoma), 25 S100 is expressed in a subset of sarcomas and may be expressed in carcinomas, especially those from the breast and salivary gland. 23,26 Melan-A (MART1) and HMB-45 are expressed in most melanomas, although expression is often lost in spindled/desmoplastic melanoma. 26 Positive staining for Melan-A or HMB-45 reasonably excludes carcinomas and most sarcomas.…”
Section: Carcinomas With Clear Cellsmentioning
confidence: 99%
“…23,26 Melan-A (MART1) and HMB-45 are expressed in most melanomas, although expression is often lost in spindled/desmoplastic melanoma. 26 Positive staining for Melan-A or HMB-45 reasonably excludes carcinomas and most sarcomas. 23 MiTF is less specific, with expression in nonmelanocytic lesions, including histiocytic lesions and cellular neurothekeoma.…”
Section: Carcinomas With Clear Cellsmentioning
confidence: 99%
“…En-face slices (parallel to the surface) are captured sequentially for increasing depths in skin and recorded as a z-stack of images (as illustrated in Figure 1). Skin biologists and clinicians are interested in the location of the dermal-epidermal junction (DEJ) in these z-stacks because disorder and disease, including cancer usually start at this boundary [8]. …”
Section: Introductionmentioning
confidence: 99%