Lens extraction for chronic angle-closure glaucoma

Predictors of long-term intraocular pressure control after lens extraction in primary angle closure glaucoma: results from the EAGLE trial

“…While no other trials describe the effect of CLE on long-term IOP outcomes in PAC or PACG to our knowledge, others also describe significant IOP reduction following standalone cataract extraction for PAC or PACG at 6 to 24 months postoperatively, between -1.8 and -8.3mmHg. [16][17][18][19] A shallower anterior chamber has been associated with greater IOP reduction after surgery for patients with PACG and cataract, 13 in agreement with findings here for those randomized to CLE. A recent study of 18 PAC patients in a tertiary centre in India undergoing cataract surgery with baseline IOP >30 mmHg found that greater preoperative iridotrabecular contact was associated with a greater proportionate drop in IOP.…”

Predictors of long-term intraocular pressure control after lens extraction in primary angle closure glaucoma: results from the EAGLE trial

“…While no other trials describe the effect of CLE on long-term IOP outcomes in PAC or PACG to our knowledge, others also describe significant IOP reduction following standalone cataract extraction for PAC or PACG at 6 to 24 months postoperatively, between -1.8 and -8.3mmHg. [16][17][18][19] A shallower anterior chamber has been associated with greater IOP reduction after surgery for patients with PACG and cataract, 13 in agreement with findings here for those randomized to CLE. A recent study of 18 PAC patients in a tertiary centre in India undergoing cataract surgery with baseline IOP >30 mmHg found that greater preoperative iridotrabecular contact was associated with a greater proportionate drop in IOP.…”

Combined Phacoemulsification, Goniosynechialysis and Ab Interno Trabeculectomy in Primary Angle-closure Glaucoma: Long-term Results

“…It has the potential to reduce IOP and the number of required antiglaucoma medications 27 . However, some studies have reported that phaco-GSL does not significantly differ from cataract surgery in terms of IOP, requirements for antiglaucoma medication, or complication rates 10 , 13 , 28 . Furthermore, Tian et al compared the outcomes of phaco-GSL in patients with acute or chronic primary angle closure (PAC) /PACG and found a higher success rate in acute patients (100% versus 64.3%) 29 .…”

“…Phaco-trabeculectomy, a combination of phacoemulsification with IOL implantation and trabeculectomy, can effectively address TM blockage and has been evaluated as a treatment option for PACG. However, it is associated with more postoperative interventions and longer recovery times 11 , 12 , 28 , 38 . High incidence of complications, including shallow anterior chamber, choroidal detachment, hypotony maculopathy and blebitis, is also a problem to be considered 9 .…”

Does standalone phacoemulsification lower intraocular pressure in glaucomatous eyes? A systematic review and meta-analysis

“…A Cochrane review by Ong et al assessed the effect of lens extraction in the treatment of chronic primary ACG. They found that phacoemulsification may not significantly lower IOP compared to standard care; however, it does offer benefits in reducing medication dependency and slowing visual field progression [ 55 ]. Benekos et al explored the effect of phacoemulsification on IOP in patients with OAG and reached a conclusion similar to ours, finding that phacoemulsification alone significantly reduces IOP in OAG patients at 1-year follow-up and beyond [ 56 ].…”

Predictors of long-term intraocular pressure control after lens extraction in primary angle closure glaucoma: results from the EAGLE trial

“…While no other trials describe the effect of CLE on long-term IOP outcomes in PAC or PACG to our knowledge, others also describe significant IOP reduction following standalone cataract extraction for PAC or PACG at 6 to 24 months postoperatively, between -1.8 and -8.3mmHg. [16][17][18][19] A shallower anterior chamber has been associated with greater IOP reduction after surgery for patients with PACG and cataract, 13 in agreement with findings here for those randomized to CLE. A recent study of 18 PAC patients in a tertiary centre in India undergoing cataract surgery with baseline IOP >30 mmHg found that greater preoperative iridotrabecular contact was associated with a greater proportionate drop in IOP.…”

Combined Phacoemulsification, Goniosynechialysis and Ab Interno Trabeculectomy in Primary Angle-closure Glaucoma: Long-term Results

“…It has the potential to reduce IOP and the number of required antiglaucoma medications 27 . However, some studies have reported that phaco-GSL does not significantly differ from cataract surgery in terms of IOP, requirements for antiglaucoma medication, or complication rates 10 , 13 , 28 . Furthermore, Tian et al compared the outcomes of phaco-GSL in patients with acute or chronic primary angle closure (PAC) /PACG and found a higher success rate in acute patients (100% versus 64.3%) 29 .…”

“…Phaco-trabeculectomy, a combination of phacoemulsification with IOL implantation and trabeculectomy, can effectively address TM blockage and has been evaluated as a treatment option for PACG. However, it is associated with more postoperative interventions and longer recovery times 11 , 12 , 28 , 38 . High incidence of complications, including shallow anterior chamber, choroidal detachment, hypotony maculopathy and blebitis, is also a problem to be considered 9 .…”

Does standalone phacoemulsification lower intraocular pressure in glaucomatous eyes? A systematic review and meta-analysis

“…A Cochrane review by Ong et al assessed the effect of lens extraction in the treatment of chronic primary ACG. They found that phacoemulsification may not significantly lower IOP compared to standard care; however, it does offer benefits in reducing medication dependency and slowing visual field progression [ 55 ]. Benekos et al explored the effect of phacoemulsification on IOP in patients with OAG and reached a conclusion similar to ours, finding that phacoemulsification alone significantly reduces IOP in OAG patients at 1-year follow-up and beyond [ 56 ].…”

Predictors of long-term intraocular pressure control after lens extraction in primary angle closure glaucoma: results from the EAGLE trial

“…While no other trials describe the effect of CLE on long-term IOP outcomes in PAC or PACG to our knowledge, others also describe significant IOP reduction following standalone cataract extraction for PAC or PACG at 6 to 24 months postoperatively, between -1.8 and -8.3mmHg. [16][17][18][19] A shallower anterior chamber has been associated with greater IOP reduction after surgery for patients with PACG and cataract, 13 in agreement with findings here for those randomized to CLE. A recent study of 18 PAC patients in a tertiary centre in India undergoing cataract surgery with baseline IOP >30 mmHg found that greater preoperative iridotrabecular contact was associated with a greater proportionate drop in IOP.…”

Combined Phacoemulsification, Goniosynechialysis and Ab Interno Trabeculectomy in Primary Angle-closure Glaucoma: Long-term Results

“…It has the potential to reduce IOP and the number of required antiglaucoma medications 27 . However, some studies have reported that phaco-GSL does not significantly differ from cataract surgery in terms of IOP, requirements for antiglaucoma medication, or complication rates 10 , 13 , 28 . Furthermore, Tian et al compared the outcomes of phaco-GSL in patients with acute or chronic primary angle closure (PAC) /PACG and found a higher success rate in acute patients (100% versus 64.3%) 29 .…”

“…Phaco-trabeculectomy, a combination of phacoemulsification with IOL implantation and trabeculectomy, can effectively address TM blockage and has been evaluated as a treatment option for PACG. However, it is associated with more postoperative interventions and longer recovery times 11 , 12 , 28 , 38 . High incidence of complications, including shallow anterior chamber, choroidal detachment, hypotony maculopathy and blebitis, is also a problem to be considered 9 .…”

Does standalone phacoemulsification lower intraocular pressure in glaucomatous eyes? A systematic review and meta-analysis

“…A Cochrane review by Ong et al assessed the effect of lens extraction in the treatment of chronic primary ACG. They found that phacoemulsification may not significantly lower IOP compared to standard care; however, it does offer benefits in reducing medication dependency and slowing visual field progression [ 55 ]. Benekos et al explored the effect of phacoemulsification on IOP in patients with OAG and reached a conclusion similar to ours, finding that phacoemulsification alone significantly reduces IOP in OAG patients at 1-year follow-up and beyond [ 56 ].…”