2012
DOI: 10.1016/j.jcma.2012.07.009
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Abstract: The current study supports for the first time the potential effectiveness of administration of IGF2 in adjusting limb length discrepancy.

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Cited by 4 publications
(2 citation statements)
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References 25 publications
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“…Experimental drug delivery approaches include surgically implanted catheters and localized injections into specific growth plates. 4,5…”
mentioning
confidence: 99%
“…Experimental drug delivery approaches include surgically implanted catheters and localized injections into specific growth plates. 4,5…”
mentioning
confidence: 99%
“…However, one persistent and major challenge is a lack of adequate methods for targeting these molecules to avascular cartilage (63). Although some experimental techniques have been successful using localized injections, catheters, and drugreleasing implants (1,5,14,45,73,89), we do not have a clear picture of how they are physically transported into cartilage. A better understanding of factors affecting molecular uptake in growth plates would enable us to better design drug delivery approaches to potentially treat a range of debilitating growth plate disorders in children.…”
mentioning
confidence: 99%