Leiomyoma of the breast: an uncommon tumor

Sampaio, Giorge Pereira; Koch, Melissa Vieira; Boechat, M. Ines; Matos, Viviane Esteves; Santos, Alair Augusto Sarmet Moreira Damas dos

doi:10.1590/0100-3984.2014.0136

Cited by 7 publications

(9 citation statements)

References 10 publications

(12 reference statements)

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“…Leiomyomas are benign mesenchymal tumours composed of smooth muscle tissue and account for the majority of mesenchymal neoplasms of the gastrointestinal tract and uterus. 1 Breast leiomyomas are extremely rare and represent less than 1% of all breast neoplasms. Only a few cases have been reported in the literature.…”

Section: Discussionmentioning

confidence: 99%

Nipple-areolar complex: commonest site of breast leiomyoma

et al. 2022

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Breast leiomyomas are extremely rare and commonly seen in the nipple-areolar complex due to the presence of smooth muscle. Identification of this rare benign tumour is based on its location and the presence of spindle cells on histology. We report a case of a breast leiomyoma in a female patient who had a six-year history of a unilateral breast mass. Breast ultrasound and mammography demonstrated a sub-areola mass and an ultrasound-guided core biopsy revealed a benign spindle cell neoplasm with smooth muscle differentiation. The lesion was excised and final histology confirmed a leiomyoma with clear margins.

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Section: Discussionmentioning

confidence: 99%

Nipple-areolar complex: commonest site of breast leiomyoma

et al. 2022

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“…1,6,7 Although typically asymptomatic, patients may present a clinically palpable painless lump, discomfort, pain, pruritus and hardening of the nipple. 4,8 On mammography, the majority of reported leiomyomas are well defined, homogenous and dense with no microcalcifications. Sonography studies showed mainly solid, well circumscribed and homogenous lesions.…”

Section: Discussionmentioning

confidence: 99%

“…Since no radiological criteria exist for the diagnose of smooth muscle neoplasm, histopathological evaluation is the definitive diagnostic method. 3,4 The common histopathological features show bundles of spindle cells with no or infrequent mitosis and immunohistochemical staining for vimentin, desmin and smooth muscle actin. 3,5,7 Also, these lesions are negative for S100 protein and cytokeratin.…”

Section: Discussionmentioning

confidence: 99%

Unanticipated diagnosis- intraparenchymal leiomyoma of the breast: case report

et al. 2020

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Smooth muscle neoplasms are uncommon, particularly if we are talking about the mammary gland. We report a case a case of a 38-year-old female with an 11.6 mm right breast nodule. A wire-guided surgical excision was performed and the histopathologic and immunohistochemical studies revealed a leiomyoma. There are no radiological criteria to allow the diagnosis of smooth muscle neoplasm and histopathological evaluation is the definitive diagnostic method. Despite being a benign neoplasm, it may mimic malignancies and therefore present a diagnostic challenge.

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“…A typical localizations of leiomyoma (breast and intracranial localization) (8, 9) are also described. We report a case of a very large leiomyoma of the urethra.…”

Section: Introductionmentioning

confidence: 99%