Left atrial myxoma complicated with multi-system embolization

Zhang, Ren-Dan; Zeng, Zhihuan; Zheng, Jianyi; Li, Tudi; Zhao, Yanqun; Liu, Yuhong; Yao, Yusi

doi:10.1186/s13019-017-0640-2

Cited by 13 publications

(14 citation statements)

References 16 publications

(15 reference statements)

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“…Most often, less obvious cardiac symptoms are discovered only after an embolism. [ 5 ] Therefore, cardiac myxomas are often misdiagnosed in the pediatric population. In the 18 previously reported pediatric cases plus our own, 10 children presented with cerebral ischemic stroke prior to diagnosis.…”

Section: Discussionmentioning

confidence: 99%

Stroke and peripheral embolisms in a pediatric patient with giant atrial myxoma

Fu²,

Liao³

et al. 2018

Medicine

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Rationale:Cerebral stroke with peripheral embolism due to left atrial myxoma is very rare in children. Misdiagnosis may occur because of nonspecific symptoms in the heart.Patient concerns:We present a case of a 16-year-old boy who presented with ischemic stroke and embolisms in the lower extremity, caused by a giant left atrial myxoma.Diagnoses:Left atrial myxoma.Interventions:A giant gelatinous mass was completely excised, and the histopathological findings confirmed the diagnosis of atrial myxoma.Outcomes:The temperature of the right lower extremity recovered gradually, and pulse of the right dorsalis pedis artery became palpable 10 days after the surgery. The strength of the bilateral lower extremity was level 5 at discharge.Lessons:Our case, along with the review of the literature, highlights the fact that myxomas often initially present with multiple embolisms but with few cardiac symptoms. Transthoracic echocardiography should be performed immediately to make a definitive diagnosis.

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Section: Discussionmentioning

confidence: 99%

Stroke and peripheral embolisms in a pediatric patient with giant atrial myxoma

Fu²,

Liao³

et al. 2018

Medicine

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“…Henceforth, this report puts emphasis on the fact that AM, though rare, should be considered as a source of embolism in patients presenting with acute limb ischemia. A case series study published in the year 2017 found that 4 out of 46 cases of left AM experienced multisystem embolization [ 15 ]. Common causes of embolism must also be excluded, including COVID-19 viral infection which is known to cause a hypercoagulable state [ 16 ].…”

Section: Discussionmentioning

confidence: 99%

A Case Report of Atrial Myxoma in the Time of Corona Presenting with Systemic Embolization

Younes

Mansour²,

Halaki

et al. 2022

Dubai Med J

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Myxomas are very rare intracardiac benign tumors. They can arise in any of the cardiac chambers, although 75% occur in the left atrium. Atrial myxomas (AMs) show a female predominance with a sex ratio of 3:1. There is a diversity in the clinical presentation; it may resemble many cardiovascular or systemic diseases. Furthermore, it is possible to present as an acute upper or lower limb ischemia or organ infarction due to systemic emboli. Hereby, we report a previously healthy 38-year-old male, who presented to the emergency department with acute pain of both lower limbs, unilateral upper limb, and acute abdomen. A bedside transthoracic echocardiogram was done which showed a mass that was confirmed to be an AM. The patient underwent surgical embolectomy and tumor resection. As this tumor is rare, the duration between the onset of symptoms to finally reaching the correct diagnosis is usually prolonged, and meanwhile, the patient can experience irreversible neurological damage or even death. Hence, we would like to highlight the role of echocardiogram in detecting AMs. In addition, excluding the primary cause of the thrombi, the patient’s ischemic pain has a spectrum of differential diagnosis ranging from peripheral vascular disease to COVID-19. We would also like to emphasize the importance of a high index of suspicion by emergency physicians when such cases present.

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“…While left atrial myxomas are more common than the right-sided counterpart and give suspicion for their presence via their distant manifestations despite other risk factors for distal embolic phenomenon, right atrial myxomas still need attention especially in the setting of PE without any or significant risk factors. 5–9 Furthermore, evidence of myocardial injury suggested an alternative diagnosis was reasonable. However, there seemed to be a disconnect between the patient’s clinical evaluation and her radiographic thrombus burden.…”

Section: Discussionmentioning

confidence: 99%

Right atrial myxoma presenting as a pulmonary embolism in a 32-year-old female

Pandey

Carey

Thompson

2019

JRSM Cardiovascular Disease

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Primary cardiac tumors are typically benign, with myxomas being most common. We present a 32-year-old female with a chief complaint of dyspnea and a constant non-radiating chest pressure along the left sternal border. She was found to have a pulmonary embolism that was ultimately caused by embolization of a right atrial myxoma with remnants of a large, highly mobile mass attached to the right inter-atrial septum prolapsing through the tricuspid valve. The patient underwent a median sternotomy, right atrial mass resection, pulmonary embolectomy, and inter-atrial septum reconstruction using the patient’s pericardium. The importance of finding the etiology of initial diagnoses is stressed with long-term outcomes for patients.

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Left atrial myxoma complicated with multi-system embolization

Cited by 13 publications

References 16 publications

Stroke and peripheral embolisms in a pediatric patient with giant atrial myxoma

Stroke and peripheral embolisms in a pediatric patient with giant atrial myxoma

A Case Report of Atrial Myxoma in the Time of Corona Presenting with Systemic Embolization

Right atrial myxoma presenting as a pulmonary embolism in a 32-year-old female

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