Lavender lactone and other volatile constituents of the oleoresin from seeds ofGarcinia kola Heckel

Medicinal Potential, Utilization and Domestication Status of Bitter Kola (Garcinia kola Heckel) in West and Central Africa

“…The pericarp of the seed is light brown-colored when fresh but darkens with drying or age. The kernel is white with brownish-red branched lines producing red resinous globules [35]. Seed length and width are on average 3.0 × 1.5 cm, mean weight varies around 5.4 g. In West and Central Africa, the fruits are ready to be harvested from April to October [39,45], but the exact period varies within regions and climate zones.…”

“…The seeds are chewed to suppress headaches, laryngitis, bronchitis, malaria, and gonorrhea [56,57]. The seed extract is used as a cure for various types of inflammation or liver cirrhosis [35], while dried ground kernels can be mixed with honey to prepare a traditional paste against cough [44]. Pharmaceutical companies from Nigeria and Cameroon have recently started to focus on small-scale production of bitter kola syrups, eye drops, or herbal pastes.…”

“…Apart from its medicinal value, the bark serves in palm wine production. It is believed that the bark enhances flavor as well as alcohol content of the traditional beverage [35,61]. In countries such as Ghana, branches and roots of G. kola are sold in bundles as an essential source of chewing sticks used for dental hygiene [31].…”

Effect of <i>Garcinia kola</i> on Atorvastatin Dissolution Profile: An Indication for Possible Drug-Drug Interactions After Oral Administration

“…G. kola is utilized in folklore medicine to treat liver disorders, hepatitis, diarrhea, laryngitis, bronchial diseases, fever, malaria and gonorrhea (Oluwatosin et al, 2014;Tauchen et al, 2023). Phytochemical analysis of G. kola reveals that the nut contains several phytochemical compounds including oleoresin (Onayade et al, 1998), tannins, saponins, alkaloids, and cardiac glycosides, bioflavonoids such as kolaflavone and 2-hydroxybiflavonols, garcinianin, kolaviron, kolanone, gakolanone, garcinoic, garcinal, benzophenones, benzofurans, benzopyran, vitamin E derivatives, xanthones, and phytosterols (Akoro et al, 2020;Emmanuel et al, 2022;Tauchen et al, 2023). Bioactivity screenings have positioned the plant as a possible source of pharmaceutically important drugs.…”