Late Paraphrenia

Herbert, M. E.; Jacobson, S.

doi:10.1192/bjp.113.498.461

Cited by 102 publications

(82 citation statements)

References 5 publications

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“…Table 3 shows general sociodemographic and clinical variables of the study sample. Female sex was overrepresented in the paranoid group which is in accordance with the findings in most other studies on late paraphrenia [3][4][5]10]; the difference, however, was not significant. The level of education 2 was significantly higher in the depressive group.…”

Section: Resultssupporting

confidence: 82%

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Life Events in Late Paraphrenia and Depression

Fuchs

1999

Psychopathology

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38 patients with late paraphrenia and 38 with endogenous depression of late onset were examined and various premorbid characteristics and biographical data compared. The main objective of the study was to look for differential risk factors and for biographical experiences that suggested a specific premorbid vulnerability in paranoid and depressive patients. In the paranoid group, a significantly higher frequency of discriminating, humiliating or threatening experiences during earlier life was found. These included expulsion from home in the years 1944–46 (53%), somatic handicaps such as amputations (13%), illegitimate birth (11%) or illegitimate children (13%), and others. In the depressed group, severe early loss prevailed (29%). The significance of these results for the etiology of late-life mental disorder is discussed.

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Section: Resultssupporting

confidence: 82%

“…64%). However, a high rate of late paraphrenic patients have prevailing hallucinations without any first-rank or negative symptoms of schizophrenia [3,5,10]…”

Section: Diagnostic Classification Of Late Paraphreniamentioning

confidence: 99%

Life Events in Late Paraphrenia and Depression

Fuchs

1999

Psychopathology

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“…11,12 Further, females have been noted to exceed males in late-onset psychosis samples by six-to ten-fold. 10,13,14 This gender imbalance is not fully explained by the greater longevity of women, and is at variance with the much closer female-to-male ratio in earlyonset schizophrenia. 10 The anti-dopaminergic effect of oestrogen has been postulated as conferring some protection for premenopausal women who are genetically predisposed to developing schizophrenia.…”

Section: Epidemiology Diagnostic Issues and Possible Risk Factorsmentioning

confidence: 97%

“…14,29 Paranoid or schizoid personality features have been described in these patients, but such retrospective assessment of premorbid adjustment is problematic as psychotic symptoms may have been present for several years. Howard & Levy 30 highlighted this methodological difficulty in their investigation of personality traits in 25 'late paraphrenia' patients.…”

Section: Epidemiology Diagnostic Issues and Possible Risk Factorsmentioning

confidence: 99%

Schizophrenia and delusional disorders with onset in later life

Hassett

2002

Rev. Bras. Psiquiatr.

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Keywords Resumo DescritoresSchizophrenia-spectrum illness is most commonly associated with an onset in early adulthood. When nonaffective psychotic symptoms emerge for the first time in later life, the clinical presentation has both similarities and differences with earlier-onset syndromes. This situation has resulted in continuing debate about the nosological status of late-onset psychosis, and whether there are particular risk factors associated with this latelife peak in incidence. Although early cognitive decline is frequently identified in these patients, studies, to date, have not established if there is a relationship with the dementing illnesses of old age. Sensory impairment, social isolation, and a family history of schizophrenia have been associated with late-onset psychosis, but appear to exert a nonspecific influence on vulnerability. While diagnostic issues remain unresolved, clinicians need to formulate treatment strategies that most appropriately address the constellation of symptoms in the clinical presentation of their psychotic elderly patients.Schizophrenia. Psychotic disorders. Psychoses. Cognition. Social isolation. Aged. Transtornos mentais do espectro da esquizofrenia são comumente associados a início na primeira fase da vida adulta. Quando sintomas psicóticos não-afetivos emergem pela primeira vez em fases tardias da vida, a apresentação clínica tem semelhanças e diferenças em relação às

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“…The tendency to con fine this diagnosis to elderly patients can be seen in Kay and Roth's [1961] paper on environmental and hereditary factors in the schizophre nias of old age. Herbert and Jacobson [1967] followed this course by confining the diagnosis to a group comprising those over sixty-five years of age. Recent studies have not attempted to distinguish within the large group of individuals showing paranoid delusions in middle or old age, points of discrimination which would allow those traditionally described as paraphrenic on the basis mainly of the systematization of their delu sional system be distinguished from those who could be more adequately described as paranoid schizophrenics.…”

Section: Introductionmentioning

confidence: 99%

Paraphrenia and Paranoid Schizophrenia

Jb¹

1969

Psychopathology

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Late Paraphrenia

Cited by 102 publications

References 5 publications

Life Events in Late Paraphrenia and Depression

Life Events in Late Paraphrenia and Depression

Schizophrenia and delusional disorders with onset in later life

Paraphrenia and Paranoid Schizophrenia

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