Latanoprost in port wine stain related paediatric glaucoma

Sturge-Weber Syndrome

“…The best studied topical medication is latanoprost, with research showing effective control of intraocular pressure in up to 50% of patients [37, 38, 39]. When medication alone is unable to reduce elevated eye pressure, it is often necessary to resort to surgery to maintain optimal eye function.…”

Results of external beam radiotherapy for diffuse choroidal hemangiomas in Sturge–Weber syndrome

“…Treatments for SWS-related glaucoma include both topical medication and surgical intervention. The most wellstudied topical medication is latanoprost (Xalatan, Catalent Pharma Solutions (part of Pfizer), Woodstock, Illinois) [26,27]. The mechanism of action of increasing uveoscleral outflow theoretically bypasses the problems of EVP affecting the natural aqueous drainage process.…”

Bilateral juvenile open angle glaucoma in two Chinese children: case report

“…The mechanism of action appears to increase uveoscleral outflow of aqueous humour and to cause a slight increase in outflow facility 26 . It is efficacious when used as adjunctive therapy and as monotherapy in adult glaucoma 27 . The therapeutic use of Xalatan on paediatric patients is controversial.…”