Laryngopharyngeal reflux finding scores correlate with gastroesophageal reflux disease and Helicobacter pylori expression

Tezer, Mesut Sabri; Koçkar, Muhammed Cem; Koçkar, Olga; Çelik, Alper

doi:10.1080/00016480500529314

Cited by 22 publications

(4 citation statements)

References 16 publications

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“…Other studies have also found that the most common laryngeal finding "as assessed by RFS" was found to be erythema/hyperemia like studies of Book et [13,14,[21][22][23][24]. Also, other authors have noted that the most common laryngoscopic signs are posterior commissure hypertrophy as by Belafsky et al and partial ventricular obliteration as by Tezer et al [11,25].…”

Section: Discussionmentioning

confidence: 86%

Proton pump inhibitors as treatment of laryngeal disorders among patients with gastroesophageal reflux disease: a single-arm (pre and post) quasi-experimental study

Ragaee

Sedik

Ahmed

et al. 2023

Egypt J Otolaryngol

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Background Laryngopharyngeal reflux is a silent cause of laryngeal disorders which was documented in the last decade by many studies. This study aimed to evaluate the prevalence of laryngeal reflux in GERD cases and to evaluate the effect of GERD treatment on these laryngeal disorders. Methodology In this single-arm (pre and post) quasi-experimental study, eighty patients with GERD were examined for laryngeal disorders by rigid laryngoscopy and assessed by the Reflux Finding Score (RFS). Complaints of patients were evaluated using the 9-item Reflux Symptom Index (RSI) questionnaire. Patients received medical treatment of GERD in the form of proton pump inhibitors (PPIs) only, and they were reassessed after 3 months for improvement in their symptoms and signs using RSI and RFS systems to compare patient complaints and findings in the laryngeal endoscopy pre- and post-treatment. Results Among 80 confirmed GERD cases, 70 (87.5%) suffered from laryngeal disorders. Throat clearing and postnasal drip were the most prevalent symptoms, and ventricular obliteration and erythema, vocal fold and diffuse laryngeal edema, and posterior commissure hypertrophy were the most detected signs. Significant improvement in both symptoms and signs after 3 months of PPI therapy was clearly observed. The resistance rate among our studied patients was reported to be 22.4%. Conclusion GERD can be considered as an inducer or cause of laryngeal disorders, with a significant direct proportional relationship between the severity of GERD and both the RSI and RFS. PPI greatly improves laryngeal disorders among GERD patients with a high response rate (77.6%).

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Section: Discussionmentioning

confidence: 86%

Proton pump inhibitors as treatment of laryngeal disorders among patients with gastroesophageal reflux disease: a single-arm (pre and post) quasi-experimental study

Ragaee

Sedik

Ahmed

et al. 2023

Egypt J Otolaryngol

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“…The mean RFS score was 9.5 in our study and more than 7 score was considered abnormal. In a study done by Tezer et al 16 , the mean RFS score was 11.5. Similarly mean score was recorded to be 10 in a study by Vardar et al 2 .…”

Section: Discussionmentioning

confidence: 91%

“…The most common presenting symptoms in our study was hoarseness (97%) followed by coughing (90.7%). The mean RSI score was 11.6±2.2 (range, [5][6][7][8][9][10][11][12][13][14][15][16][17][18][19]. The distribution of severity of each symptom among the patients was summarised in Table 1.…”

Section: Resultsmentioning

confidence: 99%

Prevalence of Laryngopharyngeal Reflux in Patients with Gastroesophageal Reflux Disease Undergoing Upper Esophagogastroduodenoscopy

Chalise

Khadka

Mukhia

et al. 2019

Journal of Institute of Medicine

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Introduction Gastroesophageal reflux disease (GERD) has been defined as the retrograde flow of gastric contents into the esophagus. Laryngopharyngeal reflux (LPR) is one of the manifestations of GERD which can be diagnosed clinically by Reflux Symptom Index (RSI) and Reflux Finding Score (RFS). The aim of this study was to find the prevalence of laryngopharyngeal reflux in patients with GERD undergoing upper esophagogastroduodenoscopy. MethodsThis was a prospective cross sectional study and all the patients visiting author’s institute with GERD undergoing upper esophagogastroduodenoscopy were included. All the relevant data on history, examination, RSI scores, RFS scores and upper esophagogastroduodenoscopy findings were recorded in the standard proforma and data were analysed. ResultsA total of 205 patients with GERD and undergoing upper esophagogastroduodenoscopy were included whose mean age was 46.1 years. The female to male ratio was 1.3:1. The most common presenting symptoms in our study was hoarseness (97%) followed by coughing (90.7%). The mean RSI score was 11.6. The symptom prevalence of LPR was 23.4%. The prevalence in between age groups and gender was not significantly different. The mean RFS score was 9.5. The prevalence of LPR by RFS assessment was 64.4%, which is significantly more than the prevalence assessed by RSI (23.4%). ConclusionThe prevalence of LPR in patients with GERD by RSI was less than the prevalence by RFS. So both the tools need to be used simultaneously to make the diagnosis and not recommendable to use independently.

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“…En cuanto a la correlación de Helicobacter pylori y laringitis por RLF, Taner y colaboradores (23) y Tezer y colaboradores (24) han concluido que la expresión de positividad de Helicobacter pylori y el grado de ERGE se correlacionaron con RLF en 45 pacientes. La positividad de Helicobacter pylori y el grado de ERGE fueron más adversos en pacientes con RLF.…”

Section: Discussionunclassified

Correlación diagnóstica entre fibrolaringoscopia y videoendoscopia digestiva alta en pacientes con reflujo gastroesofágico y reflujo laringofaríngeo

Torres-López,

Labedz,

Trakal

2022

Acta otorrinolaringol cir cabeza cuello

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Introducción: el reflujo laringofaríngeo (RLF) se origina por el flujo retrógrado de contenido gástrico hacia la faringe, pero es una entidad diferente de la enfermedad por reflujo gastroesofágico (ERGE). El objetivo del estudio fue determinar la correlación entre los signos endoscópicos de la fibrolaringoscopia y la videoendoscopia digestiva alta (VEDA). Material y métodos: estudio observacional, retrospectivo y analítico. Se incluyeron pacientes que consultaron por sintomatología de RLF y ERGE. Los hallazgos visualizados por fibrolaringoscopia flexible, VEDA y biopsia de mucosa gástrica de cada paciente se compararon con la prueba de chi-cuadrado

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Laryngopharyngeal reflux finding scores correlate with gastroesophageal reflux disease and Helicobacter pylori expression

Cited by 22 publications

References 16 publications

Proton pump inhibitors as treatment of laryngeal disorders among patients with gastroesophageal reflux disease: a single-arm (pre and post) quasi-experimental study

Proton pump inhibitors as treatment of laryngeal disorders among patients with gastroesophageal reflux disease: a single-arm (pre and post) quasi-experimental study

Prevalence of Laryngopharyngeal Reflux in Patients with Gastroesophageal Reflux Disease Undergoing Upper Esophagogastroduodenoscopy

Correlación diagnóstica entre fibrolaringoscopia y videoendoscopia digestiva alta en pacientes con reflujo gastroesofágico y reflujo laringofaríngeo

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