Laryngeal responses and airflow geometry in ALS during mechanically assisted cough

Upper Airway Assessment and Responses During Mechanically Assisted Cough

“…It was suggested that using CPF alone failed to detect upper airway collapse during negative pressure titration in MI-E, and that studying the complete exsufflation airflow curve, not just the peak value, could reveal laryngeal opening or closure. 84 When comparing flow curves and visualized laryngeal events during MI-E, preliminary findings from Andersen et al 85 indicate that efforts to cough or exhale during exsufflation affect flow curve geometry (shape). The authors were unable to link visualized laryngeal response characteristics to unique airflow geometry patterns, but recognized several MI-E airflow geometry patterns ( Figure 6).…”

“…The authors were unable to link visualized laryngeal response characteristics to unique airflow geometry patterns, but recognized several MI-E airflow geometry patterns ( Figure 6). 85 Vollsaeter et al 81 studied air-flow and pressure patterns registered by the MI-E device following the examination with TFL during ongoing MI-E, see Figure 7. Air-flow patterns registered by the MI-E device revealed altered insufflation flow geometry with the initial settings, improving after modifying the flow and pressure.…”