Laparoscopic repair for perforated peptic ulcer disease

Abstract

This systematic review suggests that a decrease in septic abdominal complications may exist when laparoscopic surgery is used to correct perforated peptic ulcer. However, it is necessary to develop more randomised controlled trials that include a greater number of patients to confirm such an assumption, guaranteeing a long learning curve for participating surgeons. With the information provided by the available clinical trials it could be said that laparoscopic surgery results are not clinically different from those of open surgery.

Laparoscopic Treatment of Perforated Peptic Ulcer: A Propensity Score-Matched Comparison of Interrupted Stitches Repair versus Knotless Barbed Suture

“…Although laparoscopic repair of PPU was documented as early as 1990, the adoption rates for this approach have been variable [ 34 ]. International studies report laparoscopic repair rates ranging from 41% to 76%, a range consistent with our previous findings [ 17 , 21 , 35 , 36 ]. Additionally, the 2020 WSES guidelines suggest the laparoscopic approach as the primary treatment for stable patients with small ulcers, provided surgeons possess the necessary skills and appropriate equipment [ 37 ].…”

Laparoscopic Treatment of Perforated Peptic Ulcer: A Propensity Score-Matched Comparison of Interrupted Stitches Repair versus Knotless Barbed Suture

“…Although laparoscopic repair of PPU was documented as early as 1990, the adoption rates for this approach have been variable [ 34 ]. International studies report laparoscopic repair rates ranging from 41% to 76%, a range consistent with our previous findings [ 17 , 21 , 35 , 36 ]. Additionally, the 2020 WSES guidelines suggest the laparoscopic approach as the primary treatment for stable patients with small ulcers, provided surgeons possess the necessary skills and appropriate equipment [ 37 ].…”

Perforated peptic ulcer (PPU) treatment: an Italian nationwide propensity score-matched cohort study investigating laparoscopic vs open approach

“…Laparoscopic repair of a PPU was described as early as 1990, but rates of adoption of this approach have been un-clear. Some international studies have reported a laparoscopic repair rate ranging from 41 to 76% and our series resulted in line with this findings [ 33 , 34 ]. Moreover, in the 2020 WSES guidelines, the laparoscopic approach is suggested to be the first-line treatment for stable patients with small ulcers as long as surgeons are familiar with the skill and appropriate equipment is available [ 35 ].…”

Mortality and Morbidity in Peptic Ulcer Perforation: A Comparison between Radical Open Repair vs Conservative Laparoscopic Repair

“…Cochrane report, 7 concerning three randomized clinical trials, found no statistically significant differences between LR and OR in the abdominal septic complications (OR 0.66; 95% CI 0.30-1.47) and pulmonary complications (OR 0.43; 95% CI 0.17-1.12).…”

Laparoscopic Treatment of Perforated Peptic Ulcer: A Propensity Score-Matched Comparison of Interrupted Stitches Repair versus Knotless Barbed Suture

“…Although laparoscopic repair of PPU was documented as early as 1990, the adoption rates for this approach have been variable [ 34 ]. International studies report laparoscopic repair rates ranging from 41% to 76%, a range consistent with our previous findings [ 17 , 21 , 35 , 36 ]. Additionally, the 2020 WSES guidelines suggest the laparoscopic approach as the primary treatment for stable patients with small ulcers, provided surgeons possess the necessary skills and appropriate equipment [ 37 ].…”

Perforated peptic ulcer (PPU) treatment: an Italian nationwide propensity score-matched cohort study investigating laparoscopic vs open approach

“…Laparoscopic repair of a PPU was described as early as 1990, but rates of adoption of this approach have been un-clear. Some international studies have reported a laparoscopic repair rate ranging from 41 to 76% and our series resulted in line with this findings [ 33 , 34 ]. Moreover, in the 2020 WSES guidelines, the laparoscopic approach is suggested to be the first-line treatment for stable patients with small ulcers as long as surgeons are familiar with the skill and appropriate equipment is available [ 35 ].…”

Mortality and Morbidity in Peptic Ulcer Perforation: A Comparison between Radical Open Repair vs Conservative Laparoscopic Repair

“…Cochrane report, 7 concerning three randomized clinical trials, found no statistically significant differences between LR and OR in the abdominal septic complications (OR 0.66; 95% CI 0.30-1.47) and pulmonary complications (OR 0.43; 95% CI 0.17-1.12).…”

Laparoscopic Treatment of Perforated Peptic Ulcer: A Propensity Score-Matched Comparison of Interrupted Stitches Repair versus Knotless Barbed Suture

“…Although laparoscopic repair of PPU was documented as early as 1990, the adoption rates for this approach have been variable [ 34 ]. International studies report laparoscopic repair rates ranging from 41% to 76%, a range consistent with our previous findings [ 17 , 21 , 35 , 36 ]. Additionally, the 2020 WSES guidelines suggest the laparoscopic approach as the primary treatment for stable patients with small ulcers, provided surgeons possess the necessary skills and appropriate equipment [ 37 ].…”

Perforated peptic ulcer (PPU) treatment: an Italian nationwide propensity score-matched cohort study investigating laparoscopic vs open approach

“…Laparoscopic repair of a PPU was described as early as 1990, but rates of adoption of this approach have been un-clear. Some international studies have reported a laparoscopic repair rate ranging from 41 to 76% and our series resulted in line with this findings [ 33 , 34 ]. Moreover, in the 2020 WSES guidelines, the laparoscopic approach is suggested to be the first-line treatment for stable patients with small ulcers as long as surgeons are familiar with the skill and appropriate equipment is available [ 35 ].…”

Mortality and Morbidity in Peptic Ulcer Perforation: A Comparison between Radical Open Repair vs Conservative Laparoscopic Repair

“…Cochrane report, 7 concerning three randomized clinical trials, found no statistically significant differences between LR and OR in the abdominal septic complications (OR 0.66; 95% CI 0.30-1.47) and pulmonary complications (OR 0.43; 95% CI 0.17-1.12).…”