“Landmark Injection” for Localization of Choroidal Lesions Using Indocyanine Green Angiography

Brucker, Alexander J.; Brant, Arthur; Nyberg, William A.

doi:10.1097/00006982-199313020-00016

Cited by 7 publications

(4 citation statements)

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“…The technical principle of the confocal scanning laser ophthalmoscope (CSLO) is identical to existing designs (1994( HRA1, 2002 HRA2, Heidelberg Engineering, Heidelberg, Germany). In brief, a single mode fibre delivers the laser light from the laser sources external to the actual scan head.…”

Section: Techniquementioning

confidence: 99%

“…ICGA provides images of stunning crisp clarity of the choroidal circulation, including dynamic images (movie) from of the uptake to the late-stage phase. [31][32][33][34] Predominantly, ICGA enables a visualization of the choroidal vessels and blood flow below the RPE. This differs significantly with FA highlighting retinal vessels above the RPE and capillary networks against the dark background of the RPE.…”

Section: Indocyanine Green Angiographymentioning

confidence: 99%

“…Confocal laser imaging technology excites the dye, avoiding a scattering of light from conventional flash light with traditional angiography. ICGA provides images of stunning crisp clarity of the choroidal circulation, including dynamic images (movie) from of the uptake to the late‐stage phase 31–34 …”

Section: Introductionmentioning

confidence: 99%

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Clinical use and research applications of Heidelberg retinal angiography and spectral‐domain optical coherence tomography – a review

Hassenstein

Meyer

2009

Clinical Exper Ophthalmology

108

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Fluorescein angiography (FA) was discovered by Nowotny and Alvis in the 1960s of the 20th century and has evolved to become the 'Gold standard' for macular diagnostics. Scanning laser imaging technology achieved enhancement of contrast and resolution. The combined Heidelberg retina angiograph (HRA2) adds novel innovative features to established fundus cameras. The principle of confocal scanning laser imaging provides a high resolution of retinal and choroidal vasculature with low light exposure providing comfort and safety for the patient. Enhanced contrast, details and image sharpness image are generated using confocality. For the visualization of the choroid an indocyanine green angiography (ICGA) is the most suitable application. The main indications for ICGA are age-related macular degeneration, choroidal polypoidal vasculopathy and choroidal haemangiomas. Simultaneous digital FA and ICGA images with threedimensional resolution offer improved diagnosis of retinal and choroidal pathologies. High-speed ICGA dynamic imaging can identify feeder vessels and retinal choroidal anastomoses, ensuring safer treatment of choroidal neovascularization. Autofluorescence imaging and fundus reflectance imaging with blue and infrared light offer new follow-up parameters for retinal diseases. Finally, the real-time optical coherence tomography provides a new level of accuracy for assessment of the angiographic and morphological correlation. The combination of various macular diagnostic tools, such as infrared, blue reflectance, fundus autofluorescence, FA, ICGA and also spectral domain optical coherence tomography, lead to a better understanding and improved knowledge of macular diseases.

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Section: Techniquementioning

confidence: 99%

Section: Indocyanine Green Angiographymentioning

confidence: 99%

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Clinical use and research applications of Heidelberg retinal angiography and spectral‐domain optical coherence tomography – a review

Hassenstein

Meyer

2009

Clinical Exper Ophthalmology

108

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“…This allowed excellent visualization of vessels in the late stages (45 minutes) of the ICG angiogram without the use of a second ("land-mark") injection of ICG dye. 5 This instrument was the first completely digital instrument to allow scanning laser video angiography. Image capture and processing is done digitally so that no information is lost at any stage of processing, image manipulation, or transmission.…”

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confidence: 99%

Simultaneous Indocyanine Green and Fluorescein Angiography Using a Confocal Scanning Laser Ophthalmoscope

Freeman¹

1998

Arch Ophthalmol

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Background: Fluorescein and indocyanine green (ICG) angiography are both useful in the diagnosis and treatment of many retinal diseases. In some cases, both tests must be performed for diagnosis and treatment; however, performing both is time-consuming and may require multiple injections. Methods: We designed a compact digital confocal scanning laser ophthalmoscope to perform true simultaneous fluorescein and ICG angiography. We report our experience using the instrument to perform 169 angiograms in 117 patients. Results: There were no unexpected adverse effects from mixing the dyes and administering them in 1 injection. An entire examination, including fundus photography, fluorescein angiography, and ICG angiography, could be performed in 45 minutes. It was possible to study differences in fluorescein patterns by comparing identically timed frames and to find cases in which ICG or fluorescein was optimal in visualizing retinal and subretinal structures. Confocal optical sections in the depth (z) dimension allowed viewing in different planes. It was possible to overlay ICG and fluorescein images or compare them side-by-side using a linked cursor. Digital transmission of the images was also performed. Conclusions: Simultaneous ICG and fluorescein angiography can be performed rapidly, safely, and conveniently. The availability of simultaneous angiography will allow critical determination of the relative advantages and disadvantages of both types of angiography.

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Indocyanine green angiography of choroidal tumors

Sallet

Amoaku

Lafaut

et al. 1995

Graefe's Arch Clin Exp Ophthalmol

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“Landmark Injection” for Localization of Choroidal Lesions Using Indocyanine Green Angiography

Cited by 7 publications

References 0 publications

Clinical use and research applications of Heidelberg retinal angiography and spectral‐domain optical coherence tomography – a review

Clinical use and research applications of Heidelberg retinal angiography and spectral‐domain optical coherence tomography – a review

Simultaneous Indocyanine Green and Fluorescein Angiography Using a Confocal Scanning Laser Ophthalmoscope

Indocyanine green angiography of choroidal tumors

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