Land-use change and rodent-borne diseases: hazards on the shared socioeconomic pathways

García‐Peña, Gabriel E.; Rubio, André V.; Mendoza, Hugo; Fernández, Miguel; Milholland, Matthew T.; Aguirre, A. Alonso; Suzán, Gerardo; Zambrana‐Torrelio, Carlos

doi:10.1098/rstb.2020.0362

Cited by 23 publications

(19 citation statements)

References 94 publications

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“…This work has found that—in the continent—certain geographic regions can present between six (Mesoamerica) and up to nine (Brazil, Bolivia, Peru and Panama) species of reservoirs. These areas are consistent with the regions, designated by Han et al ( 2015 ), as areas of high diversity and, on the other hand, areas with high rates of zoonotic risk (García-Peña et al 2021 ). These authors project risk scenarios based on anthropogenic factors such as land use, but they also consider the possible risk of exposure of the human population.…”

Section: Discussionsupporting

confidence: 86%

“…After the first outbreak in Argentina, some light was shed on the main drivers of VHFs emergence. Land use change (LUC) was considered the main driver in the emergence (Mills et al 1992 ; Charrel and de Lamberrie 2010 ), because it promotes habitat destruction and changes in the original landscape structure; which modifies community rodent structure (Suzán et al 2008 ; García-Peña et al 2021 ), then, leading to greater numbers of generalists than specialists (Murphy and Romanuk 2014 ). Generalist species have the ability to rapidly colonize more than one habitat type and achieving high population densities, thereby favoring epidemic outbreaks (Mills 2005 ; Sarute and Ross 2017 ).…”

Section: Introductionmentioning

confidence: 99%

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A Review of Mammarenaviruses and Rodent Reservoirs in the Americas

et al. 2022

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In the Americas, infectious viral diseases caused by viruses of the genus Mammarenavirus have been reported since the 1960s. Such diseases have commonly been associated with land use changes, which favor abundance of generalist rodent species. In the Americas—where the rates of land use change are among the highest worldwide—at least 1326 of all 2277 known rodent species have been reported. We conducted a literature review of studies between 1960 and 2020, to establish the current and historical knowledge about genotypes of mammarenaviruses and their rodent reservoirs in the Americas. Our overall goal was to show the importance of focusing research efforts on the American continent, since the conditions exist for future viral hemorrhagic fever (VHF) outbreaks caused by rodent-borne viruses, in turn, carried by widely distributed rodents. We found 47 species identified down to the species level, and one species identified only down to the genus level (Oryzomys sp.), reported in the Americas as reservoirs of mammarenaviruses, most these are ecological generalists. These species associate with 29 genotypes of Mammarenavirus, seven of which have been linked to VHFs in humans. We also highlight the need to monitor these species, in order to prevent viral disease outbreaks in the region.

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Section: Discussionsupporting

confidence: 86%

Section: Introductionmentioning

confidence: 99%

A Review of Mammarenaviruses and Rodent Reservoirs in the Americas

et al. 2022

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“…There is increasing awareness of the global health and economic impacts of novel zoonotic pathogen spillover, driven by the ongoing SARS-CoV-2 pandemic and previous HIV/AIDs and Spanish Influenza pandemics [1]. The number of zoonotic disease spillover events and the frequency of the emergence of novel zoonotic pathogens from rodents are predicted to increase under intensifying anthropogenic pressure driven by increased human populations, urbanisation, intensification of agriculture and climate change leading to altered rodent species assemblages [2][3][4][5]. The impact of endemic zoonoses meanwhile remains underestimated [6].…”

Section: Introductionmentioning

confidence: 99%

“…West Africa has been identified as a region at increased risk for rodent-borne zoonotic disease spillover events, the probability of these events are predicted to increase under different projected future land-use change scenarios [ 4 , 25 ]. Currently within West Africa, some rodent species are known to be involved in the transmission of multiple endemic zoonoses with large burdens on human health, these pathogens include Lassa fever, Schistosomiasis, Leptospirosis and Toxoplasmosis [ 26 , 27 ].…”

Section: Introductionmentioning

confidence: 99%

Rodent trapping studies as an overlooked information source for understanding endemic and novel zoonotic spillover

et al. 2023

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Rodents, a diverse, globally distributed and ecologically important order of mammals are nevertheless important reservoirs of known and novel zoonotic pathogens. Ongoing anthropogenic land use change is altering these species’ abundance and distribution, which among zoonotic host species may increase the risk of zoonoses spillover events. A better understanding of the current distribution of rodent species is required to guide attempts to mitigate against potentially increased zoonotic disease hazard and risk. However, available species distribution and host-pathogen association datasets (e.g. IUCN, GBIF, CLOVER) are often taxonomically and spatially biased. Here, we synthesise data from West Africa from 127 rodent trapping studies, published between 1964–2022, as an additional source of information to characterise the range and presence of rodent species and identify the subgroup of species that are potential or known pathogen hosts. We identify that these rodent trapping studies, although biased towards human dominated landscapes across West Africa, can usefully complement current rodent species distribution datasets and we calculate the discrepancies between these datasets. For five regionally important zoonotic pathogens (Arenaviridae spp., Borrelia spp., Lassa mammarenavirus, Leptospira spp. and Toxoplasma gondii), we identify host-pathogen associations that have not been previously reported in host-association datasets. Finally, for these five pathogen groups, we find that the proportion of a rodent hosts range that have been sampled remains small with geographic clustering. A priority should be to sample rodent hosts across a greater geographic range to better characterise current and future risk of zoonotic spillover events. In the interim, studies of spatial pathogen risk informed by rodent distributions must incorporate a measure of the current sampling biases. The current synthesis of contextually rich rodent trapping data enriches available information from IUCN, GBIF and CLOVER which can support a more complete understanding of the hazard of zoonotic spillover events.

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“…There is increasing awareness of the global health and economic impacts of novel zoonotic pathogen spillover, driven by the ongoing SARS-CoV-2 pandemic and previous HIV/AIDs and Spanish Influenza pandemics [1]. The number of zoonotic disease spillover events and the frequency of the emergence of novel zoonotic pathogens from rodents are predicted to increase under intensifying anthropogenic pressure driven by increased human populations, urbanisation, intensification of agriculture, climate change leading to altered rodent species assemblages [2][3][4][5]. The impact of endemic zoonoses meanwhile remains underestimated [6].…”

Section: Introductionmentioning

confidence: 99%

Rodent trapping studies as an overlooked information source for understanding endemic and novel zoonotic spillover

Simons

Attfield

Jones

et al. 2022

Preprint

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Rodents are important globally distributed reservoirs of known and novel zoonotic pathogens. Ongoing anthropogenic land use change is altering the composition of host species assemblages and modifying the risk of zoonoses spillover events. These changes mean that an understanding of the current distribution of rodent species is vital for accurately describing disease hazard and managing risk. However, available species distribution and host-pathogen association datasets (e.g. IUCN, GBIF, CLOVER) are often taxonomically and spatially biased. Here, we synthesise data from West Africa from 127 rodent trapping studies, published between 1964-2022, as an additional source of information to characterise the range and presence of important zoonotic pathogen host species in this region. We identify that these rodent trapping studies, although biased towards human dominated landscapes across West Africa, can usefully complement current rodent species distribution datasets and we calculate the discrepancies between these datasets. For five regionally important zoonotic pathogens (Arenaviridae spp., Borrelia spp., Lassa mammarenavirus, Leptospira spp. and Toxoplasma gondii), we identify host-pathogen associations that have not been previously reported in host-association datasets. These omissions have the potential for biasing estimates of current risk and drivers of zoonoses. Finally, for these five pathogen groups, we find that the proportion of a rodent hosts range that has been sampled remains small with geographic clustering. A priority of future rodent trapping studies should be to sample rodent hosts across a greater geographic range to better characterise current and future risk of zoonotic spillover events. In the interim, future studies of spatial pathogen risk informed by rodent distributions must incorporate a measure of the current sampling biases. The current synthesis of contextually rich rodent trapping data enriches available information from IUCN, GBIF and CLOVER which can support a more complete understanding of the hazard of zoonotic spillover events.

show abstract

Land-use change and rodent-borne diseases: hazards on the shared socioeconomic pathways

Cited by 23 publications

References 94 publications

A Review of Mammarenaviruses and Rodent Reservoirs in the Americas

A Review of Mammarenaviruses and Rodent Reservoirs in the Americas

Rodent trapping studies as an overlooked information source for understanding endemic and novel zoonotic spillover

Rodent trapping studies as an overlooked information source for understanding endemic and novel zoonotic spillover

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