2010
DOI: 10.1021/np1002466
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Abstract: Three new aromatic epsilon-lactones, aggregatins A (1), B (2), and C (3), a new naphthoquinone derivative, aggregatin D (4), and three known anthraquinones, 2-methylanthraquinone, 7-methoxy-2-methylanthraquinone, and 7-hydroxy-2-methylanthraquinone, were isolated from the tubers of Sinningia aggregata (Gesneriaceae). Compounds 1 and 4 and the anthraquinones showed marginal antimicrobial activity.

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Cited by 15 publications
(12 citation statements)
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“…A fingerprint of ESa together with the chemical structures of the identified compounds obtained by high-performance liquid chromatographyis is shown in Fig. 1, the detailed procedure for which was described previously [21]. …”
Section: Methodsmentioning
confidence: 99%
See 1 more Smart Citation
“…A fingerprint of ESa together with the chemical structures of the identified compounds obtained by high-performance liquid chromatographyis is shown in Fig. 1, the detailed procedure for which was described previously [21]. …”
Section: Methodsmentioning
confidence: 99%
“…S . aggregata produces essential oil, anthraquinones, and aromatic compounds with a new skeleton named aggregatin A-D [20, 21]. …”
Section: Introductionmentioning
confidence: 99%
“…Compound 2 is structurally formed by coupling of two unities of aggregatin E (3), a hemiketal with a rare carbon framework. To date three compounds of this type have been reported in the literature, namely aggregatins D-F. All have been isolated for the first time from S. aggregata, 6,16 and now were found in S. warmingii. Aggregatin E also was recently reported in S. allagophylla, 17 suggesting a close relationship among these three species.…”
Section: Discussionmentioning
confidence: 99%
“…Sinningia (60) aggregata T Aggregatin D [190] Streptocarpus (18) dunnii AP Dunnione, a-dunnione, 7-hydroxy-a-dunnione, 7-methoxy-adunnione, 6-hydroxy-7-methoxy-a-dunnione [191,192] Scrophulariaceae (87) Capraria (7) biflora L 6,9-Dimethyl-3-(4-methyl-3-pentenyl)naphtho[1,8-bc]pyran-7,8-dione (biflorin) [193][194][195] Lamiaceae (250) Tectona (3) grandis HW Lapachol, deoxylapachol, tectoquinone, tecomaquinone-1,5hydroxylapachol [196][197][198][199] Salvia (959) columbariae R Miltionone II, cryptotanshinone, tanshinone IIA [22] miltiorrhiza R Tanshinones [200,201] Paulowniaceae [202,203] Pedaliaceae (11) [204,205] Bignoniaceae (85) Catalpa (11) ovata S Catalpol, catalpalactone, a-lapachone, dehydro-a-lapachone, 9-hydroxy-a-lapachone, 4,9-dihydroxy-a-lapachone, 9-methoxy-a-lapachone, 4-oxo-a-lapachone, 9-methoxy-4-oxo-a-lapachone [206][207][208] Cybistax (1) antisyphilitica SW Lapachol [209] Dolichandra ( …”
Section: Distribution Of Naphthoquinones Within the Plant Kingdommentioning
confidence: 99%