2017
DOI: 10.1080/10408398.2017.1381583
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Abstract: Lactoferrin (LF) is a multifunctional protein occurring in many biological secretions including milk. It possesses iron binding/transferring, antibacterial, antiviral, antifungal, anti-inflammatory and anti-carcinogenic properties. These functional properties intimately depend on the structural integrity of LF especially its higher order conformation. LF is primarily extracted from bovine milk and it is subsequently added into many commercial products such as nutritional supplements, infant formula, cosmetics … Show more

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Cited by 270 publications
(205 citation statements)
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“…Additionally, it is difficult to preserve during infant formula production due to denaturing at high temperatures. 27,28 Commercially added lactoferrin has similar bioactive properties as human lactoferrin. When lactoferrin was added to infant formula, it was found that the incidence of respiratory illnesses decreased while hematocrit increased.…”
Section: Novel Bioactives Protein Contentmentioning
confidence: 99%
“…Additionally, it is difficult to preserve during infant formula production due to denaturing at high temperatures. 27,28 Commercially added lactoferrin has similar bioactive properties as human lactoferrin. When lactoferrin was added to infant formula, it was found that the incidence of respiratory illnesses decreased while hematocrit increased.…”
Section: Novel Bioactives Protein Contentmentioning
confidence: 99%
“…Lactoferrin has been used in a wide variety of products since it was first added to infant formula in 1986 (Tomita et al, 2002). Now it was added into many commercial products such as cosmetics, nutritional supplements, and toothpaste (Wang et al, 2019). The antimicrobial activity of lactoferrin is mainly explained by two mechanisms; the first one is the absorption of the iron from the infection sites which is the food source of the microorganisms.…”
Section: Introductionmentioning
confidence: 99%
“…Utilizing LF by combining its multifunctional properties with nanotechnology can be a remarkable therapeutic agent [14]. Several approaches are available to synthesized LF-NPs including thermal treatment, phase separation, emulsion templating, and adsorption methods [15]. Also, understanding the bioactive compound release mechanisms is essential for predicting the behavior of lactoferrin nanoparticles during food production or food consumption.…”
Section: Introductionmentioning
confidence: 99%