Lactobacillus Strains and Vaginal Ecology

Impact of Probiotic SYNBIO® Administered by Vaginal Suppositories in Promoting Vaginal Health of Apparently Healthy Women

“…Thus, one cannot and should not utilize the data from one strain to infer that another untested strain will provide the same benefits. Several clinical studies seem to provide evidence that in lots of cases using selected lactobacilli strains the vagina could be effectively recolonized obtaining also a lower rate of BV recurrences [1,4,12,32]. In the present study, the RAPD analysis demonstrated the presence of both administered strains, in the vagina after 7 days of treatment at the same concentration while, at the end of follow-up, the concentration of IMC 501 was higher than that of IMC 502.…”

In Vitro Activities of the New Semisynthetic Glycopeptide Telavancin (TD-6424), Vancomycin, Daptomycin, Linezolid, and Four Comparator Agents against Anaerobic Gram-Positive Species and Corynebacterium spp

“…Some Lactobacillus spp. have been associated with bacteremia and endocarditis for which therapy may be problematic; others have been associated with vaginal health, while depletion has been associated with an increased risk of urinary tract infections and bacterial vaginosis (1,12,14). In our study, many Lactobacillus species that were resistant to vancomycin, linezolid, and daptomycin were generally susceptible to telavancin at concentrations of Յ0.25 g/ml.…”

Efficacy of High-dose Lactobacillus rhamnosus GG in Controlling Acute Watery Diarrhea in Indian Children

“…33 A final theory is that lactobacilli produce substances that inactivate the viral particles. This has been shown in vitro, 34 with supernatants from L. rhamnosus GR-1 and L. fermentum RC-14 inactivating 10 9 particles of the double-stranded DNA adenovirus and the negative-stranded RNA vesicular stomatitis virus within 10 minutes. More detailed mechanistic research is needed to understand how probiotic strains reduce the duration of diarrhea in conjunction with rehydration therapy.…”