Lactobacillus reuteri in bovine milk fermented decreases the oral carriage of mutans streptococci

Nikawa, Hiroki; Makihira, Seicho; Fukushima, H.; Nishimura, Haruki; Ozaki, Y.; Ishida, Kazuhiro; Darmawan, Saptadi; Hamada, Takashi; Hara, Kumiko; Matsumoto, Akane; Takemoto, Tsuyoshi; Aimi, R.

doi:10.1016/j.ijfoodmicro.2004.03.006

Cited by 193 publications

(175 citation statements)

References 15 publications

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“…Another study by Nikawa et al [23] revealed that consumption of yogurt containing L. reuteri in different concentrations reduced S. mutans in the oral cavity. They pointed out that L. reuteri was three times more effective than other lactobacilli and reported a mortality of 90 % for S. mutans.…”

Section: Discussionmentioning

confidence: 96%

“…Ç aglar et al [22] reported in in vivo studies that levels of S. mutans in saliva were positively reduced without antagonistic effects in the presence of L. reuteri contained in tablets at a concentration of 1 9 10 9 CF U/mL. Another study [23] showed that consumption of yogurts containing L. reuteri at different concentrations reduced S. mutans in the oral cavity.…”

Section: Introductionmentioning

confidence: 99%

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Antimicrobial Effect of Lactobacillus reuteri on Cariogenic Bacteria Streptococcus gordonii, Streptococcus mutans, and Periodontal Diseases Actinomyces naeslundii and Tannerella forsythia

Baca-Castañón

Garza-Ramos

Alcázar-Pizaña

et al. 2014

Probiotics & Antimicro. Prot.

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Lactic acid bacteria (LAB) are well known for their beneficial effects on human health in the intestine and immune system; however, there are few studies on the impact they can generate in oral health. The aim of this study was to test and compare in vitro antimicrobial activity of L. reuteri on pathogenic bacteria involved in the formation of dental caries: S. mutans, S. gordonii, and periodontal disease: A. naeslundii and T. forsythia. Also, we determined the growth kinetics of each bacterium involved in this study. Before determining the antimicrobial action of L. reuteri on cariogenic bacteria and periodontal disease, the behavior and cell development time of each pathogenic bacterium were studied. Once the conditions for good cell growth of each of selected pathogens were established according to their metabolic requirements, maximum exponential growth was determined, this being the reference point for analyzing the development or inhibition by LAB using the Kirby Bauer method. Chlorhexidine 0.12 % was positive control. L. reuteri was shown to have an inhibitory effect against S. mutans, followed by T. forsythia and S. gordonii, and a less significant effect against A. naeslundii. Regarding the effect shown by L. reuteri on the two major pathogens, we consider its potential use as a possible functional food in the prevention or treatment of oral diseases.

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Section: Discussionmentioning

confidence: 96%

Section: Introductionmentioning

confidence: 99%

Antimicrobial Effect of Lactobacillus reuteri on Cariogenic Bacteria Streptococcus gordonii, Streptococcus mutans, and Periodontal Diseases Actinomyces naeslundii and Tannerella forsythia

Baca-Castañón

Garza-Ramos

Alcázar-Pizaña

et al. 2014

Probiotics & Antimicro. Prot.

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“…8,21,22,23 Some studies of the effects of lactobacillus-based probiotics on mutans streptococci reported significant reductions in the levels of salivary mutans streptococci immediately after terminating daily intake. 8,21,22,23 The post-treatment reductions were not directly dependent on the delivery vehicles, which included milk, cheese, yogurt, lozenges, and straws prepared with freeze-dried strains. Çaglar et al 8 investigated whether slowly melting tablets facilitate a more thorough contact between the probiotic and the oral environment compared with a direct swallowing pattern from a straw.…”

Section: Discussionmentioning

confidence: 99%

Effects of probiotic fermented milk on biofilms, oral microbiota, and enamel

et al. 2015

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The aim of this study was to evaluate in vitro and in vivo the effects of 2 brands of probiotic fermented milk on biofilms, oral microbiota, and enamel. For the in situ experiment, ten volunteers wore palatine devices containing four blocks of bovine dental enamel over 3 phases, during which 20% sucrose solution, Yakult ® (Treatment A), and Batavito ® (Treatment B) were dropped on the enamel blocks. Salivary microbial counts were obtained and biofilm samples were analyzed after each phase. For the in vivo experiment, the same ten volunteers drunk Yakult ® (Treatment C) and Batavito ® (Treatment D) in two phases. Saliva samples were collected for microbial analysis after each phase. The in situ study showed that in comparison with Treatment A, Treatment B resulted in fewer total cultivable anaerobes and facultative microorganisms in biofilms, higher final microhardness, lower percentage change in surface hardness, and smaller integrated subsurface enamel hardness. In the in vivo study, Treatment D resulted in a reduction in the counts of all microorganisms. The results suggested that the probiotic fermented milk Batavito ® , but not Yakult ® , reduced the amount of oral microorganisms and mineral loss in bovine enamel.

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“…Lozenges containing L. brevis CD2 taken by school children with a high caries risk, resulted in a reduction in plaque acidogenicity, salivary mutans-streptococci and bleeding on probing [69]. L. reuteri significantly inhibited the growth of S. mutans, if applied as yoghurt [70], via straws and tablets [71,72] or as chewing gum [73]. A combination of L. sporogens, L. bifidum, L. bulgaricus, L. thermophilus, L. acidophilus, L. casei and L. rhamnosus either as capsule or as liquid form was tested.…”

Section: Thereforementioning

confidence: 99%

Lactobacilli for the Treatment of Oral Diseases

Hoffmann¹,

Daniels²

2017

J Prob Health

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Probiotics are defined as live microorganisms that beneficially affect the host. Probiotic bacteria have been used therapeutically for years to target gastrointestinal disease by rebalancing the complex microflora. Besides the gastrointestinal tract also the oral cavity is highly colonized by bacteria and many different bacterial species are part of the microbiota in the mouth, as it offers ideal conditions for bacteria with a stable temperature, moist surface with a relatively stable pH and regular supply of nutrients. By disturbing the balance of microorganisms in the oral cavity or by extensive accumulation of plaque, the ratio of pathogenic organisms can increase and lead to oral health problems. Probiotic bacteria, like lactobacilli, are a promising treatment strategy for oral diseases with a microbiological aetiology. Those include plaqueassociated diseases like dental caries, which is an infectious disease with microbial processes eroding and destroying the hard dental tissue or inflammation of periodontal tissue, namely gingivitis and the more severe periodontitis. Moreover, endodontic infections, and even fungal, viral and acute bacterial infections could be treated by a probiotic therapy. The interest of probiotics in the field of oral health is growing, although it is still in its infancy. The present review adresses criteria for the selection of probiotic lactobacilli strains. It encompasses existing evidence on the use of lactobacilli for caries, halitosis and candidiasis, as well as for periodontal disease like Gingivitis and periodontitis.

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Lactobacillus reuteri in bovine milk fermented decreases the oral carriage of mutans streptococci

Cited by 193 publications

References 15 publications

Antimicrobial Effect of Lactobacillus reuteri on Cariogenic Bacteria Streptococcus gordonii, Streptococcus mutans, and Periodontal Diseases Actinomyces naeslundii and Tannerella forsythia

Antimicrobial Effect of Lactobacillus reuteri on Cariogenic Bacteria Streptococcus gordonii, Streptococcus mutans, and Periodontal Diseases Actinomyces naeslundii and Tannerella forsythia

Effects of probiotic fermented milk on biofilms, oral microbiota, and enamel

Lactobacilli for the Treatment of Oral Diseases

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