2021
DOI: 10.1590/0102-672020210001e1579
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Abstract: Background: In the last decades, numerous studies have confirmed the importance of lactate - by-product to the nutrient signal of the intracellular redox state - to regulatory functions in energy metabolism. Aim: To evaluate changes in blood lactate in patients with severe obesity and its correlation with body composition and metabolic profile. Methods: Twenty-four people with severe obesity (BMI=40 kg/m2) were evaluated in a prospective case-control study before and six months after Roux-in-Y gastric by… Show more

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Cited by 5 publications
(7 citation statements)
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References 35 publications
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“…Another problem related to prolonged preoperative fasting is increased insulin resistance, which enhances the metabolic response to surgical trauma. This result is commonly observed on the first and the second day after surgery, and it is directly proportional to the operation complexity 13 .…”
Section: Introductionmentioning
confidence: 80%
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“…Another problem related to prolonged preoperative fasting is increased insulin resistance, which enhances the metabolic response to surgical trauma. This result is commonly observed on the first and the second day after surgery, and it is directly proportional to the operation complexity 13 .…”
Section: Introductionmentioning
confidence: 80%
“…O besity is a hard-treatment chronic disease that has become a global epidemic that causes health issues for individuals and society. Although there is evidence of metabolically healthy obesity 13 , there is consensus about its harms, especially about the cardiovascular risks present in obese individuals with fat deposition in the visceral region, as shown in some longitudinal studies 13 .…”
Section: Introductionmentioning
confidence: 99%
“…Unfortunately, it is increasing worldwide 22 . Obesity should not be thought of as a single disorder as it is related to many disorders like hypertension, diabetes, obstructive sleep apnea, cardiovascular diseases, metabolic alterations, gastroesophageal reflux and increased risk of malignancies 9 , 13 , 28 , 29 . For years people have struggled with obesity with both metabolic and physical problems.…”
Section: Introductionmentioning
confidence: 99%
“…Existem vários escores clínicos baseados principalmente em marcadores bioquímicos que podem ser usados para avaliar o status do fígado em pacientes com obesidade severa 7 . O índice de esteatose hepática (HSI) é uma ferramenta de triagem para o diagnóstico de esteatose 15 .…”
Section: Introductionunclassified