Abstract:The capability to image subtle mechanical motion at cellular and sub-cellular scales can be used to study how extracellular particles interact with cultured cells and, more generally, how cells interact with their environment. However, current technologies need to provide sufficient spatial resolution, temporal resolution, and motion sensitivity to image cellular and sub-cellular motion in the en face plane. To address this unmet need, we investigate a full-field Doppler phase microscopy (FF-DPM) technology ba… Show more
“…After the treatment of 3a and LED light, we also monitored the morphology change of the cells using optically computed phase microscopy that quantitatively measures the thickness of cells. 38,39 Apparent rounding and increase in height were observed for the treated samples compared with the untreated ones that were elongated and flat (Fig. S22, ESI†).…”
“…After the treatment of 3a and LED light, we also monitored the morphology change of the cells using optically computed phase microscopy that quantitatively measures the thickness of cells. 38,39 Apparent rounding and increase in height were observed for the treated samples compared with the untreated ones that were elongated and flat (Fig. S22, ESI†).…”
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