Abstract:Meta-analysis showed that lower knee extensor strength is associated with an increased risk of symptomatic and functional deterioration, but not tibiofemoral JSN. The risk of patellofemoral deterioration in the presence of knee extensor strength deficits is inconclusive.
“…16 We chose to distinguish between high and low quality in line with another similar article, with a cut-off score of >60%, which in this case was a score of >8. 18 The results are only valid for this systematic review, and should not be directly transferred to other contexts, or interpreted as the truth.…”
“…Studies with a score ≥8 (>60% of the maximal attainable score) were classified as high quality according to another systematic review from our group. 18 Two authors scored the studies independently, and then the scores were compared (MML and LE; MML and KS; MML and MAR). In cases of disagreement, the authors tried to achieve consensus.…”
Section: Study Methodological Quality Assessmentmentioning
BackgroundThis updated systematic review reports data from 2009 on the prevalence, and risk factors, for knee osteoarthritis (OA) more than 10 years after anterior cruciate ligament (ACL) tear.MethodsWe systematically searched five databases (PubMed, EMBASE, AMED, Cinahl and SPORTDiscus) for prospective and retrospective studies published after 1 August 2008. Studies were included if they investigated participants with ACL tear (isolated or in combination with medial collateral ligament and/or meniscal injuries) and reported symptomatic and/or radiographic OA at a minimum of 10 years postinjury. We used a modified version of the Downs and Black checklist for methodological quality assessment and narrative synthesis to report results. The study protocol was registered in PROSPERO.ResultsForty-one studies were included. Low methodological quality was revealed in over half of the studies. At inclusion, age ranged from 23 to 38 years, and at follow-up from 31 to 51 years. Sample sizes ranged from 18 to 780 participants. The reported radiographic OA prevalence varied between 0% and 100% >10 years after injury, regardless of follow-up time. The studies with low and high methodological quality reported a prevalence of radiographic OA between 0%–100% and 1%–80%, respectively. One study reported symptomatic knee OA for the tibiofemoral (TF) joint (35%), and one study reported symptomatic knee OA for the patellofemoral (PF) joint (15%). Meniscectomy was the only consistent risk factor determined from the data synthesis.ConclusionRadiographic knee OA varied between 0% and 100% in line with our previous systematic review from 2009. Symptomatic and radiographic knee OA was differentiated in two studies only, with a reported symptomatic OA prevalence of 35% for the TF joint and 15% for PF joint. Future cohort studies need to include measurement of symptomatic knee OA in this patient group.PROSPERO registration numberCRD42016042693.
“…16 We chose to distinguish between high and low quality in line with another similar article, with a cut-off score of >60%, which in this case was a score of >8. 18 The results are only valid for this systematic review, and should not be directly transferred to other contexts, or interpreted as the truth.…”
“…Studies with a score ≥8 (>60% of the maximal attainable score) were classified as high quality according to another systematic review from our group. 18 Two authors scored the studies independently, and then the scores were compared (MML and LE; MML and KS; MML and MAR). In cases of disagreement, the authors tried to achieve consensus.…”
Section: Study Methodological Quality Assessmentmentioning
BackgroundThis updated systematic review reports data from 2009 on the prevalence, and risk factors, for knee osteoarthritis (OA) more than 10 years after anterior cruciate ligament (ACL) tear.MethodsWe systematically searched five databases (PubMed, EMBASE, AMED, Cinahl and SPORTDiscus) for prospective and retrospective studies published after 1 August 2008. Studies were included if they investigated participants with ACL tear (isolated or in combination with medial collateral ligament and/or meniscal injuries) and reported symptomatic and/or radiographic OA at a minimum of 10 years postinjury. We used a modified version of the Downs and Black checklist for methodological quality assessment and narrative synthesis to report results. The study protocol was registered in PROSPERO.ResultsForty-one studies were included. Low methodological quality was revealed in over half of the studies. At inclusion, age ranged from 23 to 38 years, and at follow-up from 31 to 51 years. Sample sizes ranged from 18 to 780 participants. The reported radiographic OA prevalence varied between 0% and 100% >10 years after injury, regardless of follow-up time. The studies with low and high methodological quality reported a prevalence of radiographic OA between 0%–100% and 1%–80%, respectively. One study reported symptomatic knee OA for the tibiofemoral (TF) joint (35%), and one study reported symptomatic knee OA for the patellofemoral (PF) joint (15%). Meniscectomy was the only consistent risk factor determined from the data synthesis.ConclusionRadiographic knee OA varied between 0% and 100% in line with our previous systematic review from 2009. Symptomatic and radiographic knee OA was differentiated in two studies only, with a reported symptomatic OA prevalence of 35% for the TF joint and 15% for PF joint. Future cohort studies need to include measurement of symptomatic knee OA in this patient group.PROSPERO registration numberCRD42016042693.
“…Knee extensor weakness is a typical feature of knee OA 13,14 , and is associated with the development of symptomatic knee OA 15 as well as functional decline over time in people with knee OA 16 . Evidence from observational 17,18 and preepost exercise studies 19e22 reports associations between change in knee extensor muscle strength and change in pain 20e22 and self-reported physical function 17e20 in people with knee OA 17e22 or at risk for knee OA 17 .…”
Increased knee extensor strength partially mediates the effect of a knee extensor strength training program on pain and physical function improvement in people with knee OA.
“…Studies of individuals with knee osteoarthritis (OA) and those at risk of OA have shown that quadriceps weakness is strongly associated with functional limitations . For these individuals, addressing quadriceps strength often becomes a major target of rehabilitation interventions, including general aerobic and local strengthening exercises, with the hope of improving physical function, reducing pain and physical disability, and avoiding further progression of OA .We explored quadriceps strength and physical function in individuals with knee osteoarthritis from the Multicenter Osteoarthritis Study.We found evidence of strength thresholds for functional tasks that involve the body acting against gravity, such as walking or rising from a chair, in women but not in men.These thresholds in strength may provide a means of identifying individuals at the brink of disability, for whom increments in strength may be associated with improvements in physical function or greater ease in carrying out common tasks in daily life; for individuals above the strength threshold, focus should be on maintaining strength.…”
In persons with symptomatic knee OA, thresholds in the strength function relationship may help identify individuals, especially women, at the brink of disability insofar as strength and daily tasks. In those with low strength, small increments in strength may be associated with improvement in function and greater ease with common daily life, emphasizing the importance of preventing loss of strength. This article is protected by copyright. All rights reserved.
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