1963
DOI: 10.1001/archderm.1963.01590180060011
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Keratosis Follicularis of Sudden Onset

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“…The disease runs a chronic relapsing course with spontaneous remissions. Exacerbations have been reported following steroids (Witten and Gelfarb, 1963) and exposure to ultra violet radiation. Patients have an increased susceptibility to viral infections and chronic pyogenic infections (Marks et al, 1978).…”
Section: Discussionmentioning
confidence: 99%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
“…The disease runs a chronic relapsing course with spontaneous remissions. Exacerbations have been reported following steroids (Witten and Gelfarb, 1963) and exposure to ultra violet radiation. Patients have an increased susceptibility to viral infections and chronic pyogenic infections (Marks et al, 1978).…”
Section: Discussionmentioning
confidence: 99%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
“…The findings of the multiple histological examinations in both our patients are diagnostic of Darier's disease (Pinkus & Mehregan, 1969). The cases differ, however, in some important aspects from patients with Darier's disease: (i) Onset in advanced age is rare although it does not exclude this diagnosis (Ebling & Rook, 1972;Fishman, 1975;Witten, 1963). (2) Our cases exhibited rapid spread of lesions, unlike the slow spread over years usually seen in Darier's disease (Svendsen& Albrectsen, 1959)-It should be noted that they had not been exposed to sunlight shortly before or after the onset, a known provoking factor (Svendsen & Albreasen, 1959).…”
Section: Discussionmentioning
confidence: 99%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.