Keratoacanthoma of the conjunctiva

Keratoacanthoma generally occurs on the skin; it is rarely found in the conjunctiva. A case of a 34-year-old woman with a rapidly growing conjunctival mass is reported. The tumor was excised with a safety margin to exclude squamous cell carcinoma. Histopathologically it was crateriform and consistent with atypical keratoacanthoma. There has been no recurrence in 2 years of follow-up. Conjunctival keratoacanthoma is rare; differential diagnosis of conventional squamous cell carcinoma and keratoacanthoma can be difficult. We recommend complete surgical excision and careful follow-up of crateriform squamous proliferations.

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“…The first case of conjunctival KA was described by Freeman et al 5 in 1961. Only 15 cases have been described to date 4 .…”

Section: Discussionmentioning

confidence: 99%

“…It is characterized by rapid growth (4-8 weeks) and may regress spontaneously. There are only 15 reported cases related to the conjunctiva [1][2][3][4] . We describe a case of conjunctival KA and discuss the clinical and pathological findings.…”

mentioning

confidence: 99%

Conjunctival keratoacanthoma

et al. 2004

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“…Fifty years later, less than 20 cases have been described 2. KA of the skin is a much more common lesion with an incidence of 22–150 per 100 000 depending on geographic location.…”

Section: Discussionmentioning

confidence: 99%

“…Conjunctival KA is a white hyperkeratotic lesion,1 which arguably belongs to the same spectrum. While rare on the conjunctiva, it is similar to skin lesions in that KA has a characteristic rapid progression of growth (2–8 weeks) 2 3. Conjunctival melanoma can present in 20% of the cases as an amelanotic firm mass that may be accompanied by feeder vessels 4 5.…”

Section: Answers (For Questions See 275)mentioning

confidence: 99%

Conjunctival keratoacanthoma

et al. 2013

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An 83-year-old man presented with a 1-month history of a rapidly enlarging conjunctival mass. On examination, slit lamp biomicroscopy revealed a leukoplakic tumour at the temporal limbus. The lesion was excised with cryotherapy application to the limbus and conjunctival margins. Histopathology revealed a keratoacanthoma (KA). KA typically occurs on sun-exposed areas of the skin. Conjunctival KA is very rare, and differentiation between conventional squamous cell carcinoma (SCCA) and KA can be challenging. The present case highlights the indication for excisional surgery in patients with conjunctival KA using the no touch technique, cryotherapy, amniotic membrane and the histopathological differentiation between KA and SCCA.

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“…The first case of conjunctival KA was described by Freeman et al (4) , and only a few cases have been described to date (5)(6)(7) . Most of the documented cases have been found on the temporal bulbar conjunctiva within the palpebral aperture and adjacent to the limbus.…”

Section: Di̇scussi̇onmentioning

confidence: 99%