Abstract:currently ~2300 cases and ~4200 controls), to study risk factors and possible gene-environment interactions; international pooling of case-control studies; using existing cohorts (e.g. EPIC) ; and aiming to register all Dutch ALS cases. Consistent positive associations between smoking and ALS were observed within PAN and EPIC, indicating that a similar approach for occupational risk factors would be informative. Because each study design has its advantages and disadvantages , neurodegenerative disorders should… Show more
“…This method does not intend to identify new occupational risks, but may improve estimates for the most common agents known or suspected to have an adverse effect on work-related asthma till now 3 4. We developed the OAsJEM for the two-digit to four-digit ISCO-88 job codes, the most commonly used classification in Europe 34. However, the ISCO-88 classification was originally defined for economic statistical purposes, which may not be optimal for evaluation of occupational exposures.…”
The OAsJEM developed to improve occupational exposure assessment may improve evaluations of associations with asthma in epidemiological studies and contribute to assessment of the burden of work-related asthma.
“…This method does not intend to identify new occupational risks, but may improve estimates for the most common agents known or suspected to have an adverse effect on work-related asthma till now 3 4. We developed the OAsJEM for the two-digit to four-digit ISCO-88 job codes, the most commonly used classification in Europe 34. However, the ISCO-88 classification was originally defined for economic statistical purposes, which may not be optimal for evaluation of occupational exposures.…”
The OAsJEM developed to improve occupational exposure assessment may improve evaluations of associations with asthma in epidemiological studies and contribute to assessment of the burden of work-related asthma.
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