«Janus»-like Cu-Fe bimetallic nanoparticles with high antibacterial activity

Бакина, О. В.; Глазкова, Е. А.; Svarovskaya, N. V.; Rodkevich, Nikolay; Лернер, М. И.

doi:10.1016/j.matlet.2019.01.105

Cited by 31 publications

(18 citation statements)

References 17 publications

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“…Generally, the most extensively studied metals for such binary systems were Ag, Au, Pd and Pt 9 , 10 . However, the genotoxicity and cytotoxicity effects of these metals on humans and also their high cost limit their application, biologically in particular, as noted by Das et al 11 and Bakina et al 12 . Therefore, it became necessary to substitute those metals with alternatives selected on the merits of safety, easy availability, catalytic properties, cost-effectiveness, reactivity, and overall performance as pointed out by Pinto et al 13 .…”

Section: Introductionmentioning

confidence: 99%

Unveiling the role of novel biogenic functionalized CuFe hybrid nanocomposites in boosting anticancer, antimicrobial and biosorption activities

Eltarahony

Abu‐Serie

Hamad

et al. 2021

Sci Rep

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The quest for eco-friendly and biocompatible nanoparticles (NPs) is an urgent issue in the agenda of the scientific community and applied technology, which compressing synthesis routes. For the first time, a simple route for the biosynthesis of functionalized CuFe-hybrid nanocomposites (FCFNCs) was achieved using Streptomyces cyaneofuscatus through a simultaneous bioreduction strategy of Cu and Fe salts. The suitability of FCFNCs was evaluated medically and environmentally as an anticancer agent, antimicrobial agent and dye bio-sorbent. The physicochemical characteristics of FCFNCs using XRD, EDX, elemental mapping, FTIR, UV–Vis., TEM and ζ-potential confirmed the formation of spheres agglomerated into chains (37 ± 2.2 nm), self-functionalized nanocomposite by proteinaceous moieties with considerable stability (− 26.2 mV). As an anticancer agent, FCFNCs displayed the highest apoptotic impact (> 77.7%) on Caco-2, HepG-2, MCF-7 and PC-3 cancer cells at IC50 ≤ 17.21 μg/mL with the maximum up regulation of p53 and caspase 3 expression and the lowest Ki-67 level, relative to both functionalized CuNPs (FCNPs) and FeNPs (FFNPs). Meanwhile, it maintained the viability of normal human cells by EC100 up to 1999.7 μg/mL. Regarding the antimicrobial activity, FCFNCs offered > 70% growth reduction among wide spectrum prokaryotic and eukaryotic pathogens. Additionally, the synergistic feature of FCFNCs disintegrated the pre-established biofilm and algal growth in a dose-dependent manner. However, as a bio-sorbent, FCFNCs decolorized > 68% of malachite green and congo red dyes (200 mg/L), reflecting considerable remediation efficiency, confirmed by FTIR of FCFNCs- adsorbed dyes and microtoxicity/cytotoxicity of solutions after remediation. This study offers new insights into promising CuFe-hybrid nanocomposites for recruitment in several applications.

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Section: Introductionmentioning

confidence: 99%

Unveiling the role of novel biogenic functionalized CuFe hybrid nanocomposites in boosting anticancer, antimicrobial and biosorption activities

Eltarahony

Abu‐Serie

Hamad

et al. 2021

Sci Rep

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“…Copper ions (Cu 2+ ) are the form of copper that kills bacteria (Ref 14 , 15 ). Figure 10 shows a schematic diagram of Cu 2+ killing bacteria.…”

Section: Test Results and Discussionmentioning

confidence: 99%

“…When the copper content exceeded a certain level (approximately 1.2%), good antibacterial performance was obtained. The antibacterial function can be attributed to the presence of Cu 2+ , which can kill Escherichia coli and Staphylococcus aureus (Ref 14 , 15 ). Thus, Cu solid solution into a matrix cannot provide the antibacterial function unless copper is precipitated and grown to a certain size (Ref 16 , 17 ).…”

Section: Introductionmentioning

confidence: 99%

Morphology and Antibacterial Properties of Copper Precipitates in Ferrite Stainless Steel

Yin

et al. 2021

J. of Materi Eng and Perform

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“…Furthermore, Li et al [88] indicated that bacteria such as E. coli, B. subtilis, Aspergillus, Rhizopus, Penicillium, S. aureus, and yeast responded exceptionally well to the antimicrobial effect of the CS/Ag/ZnO film combinations. More importantly, the chelating function among different NPs might also affect by the antimicrobials efficacy of separate NPs [109,110,111,112]. As indicated by Lungu et al [111], AgNPs appeared to improve the antibacterial properties of both Ag-ZnO NPs without UV radiation.…”

Section: Antimicrobial Activity and Mechanism Of Ecf With Npmentioning

confidence: 99%

Antimicrobial Nanoparticles Incorporated in Edible Coatings and Films for the Preservation of Fruits and Vegetables

et al. 2019

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Edible coatings and films (ECF) are employed as matrixes for incorporating antimicrobial nanoparticles (NPs), and then they are applied on the fruits and vegetables to prolong shelf life and enhance storage quality. This paper provides a comprehensive review on the preparation, antimicrobial properties and mechanisms, surface and physical qualities of ECF containing antimicrobial NPs, and its efficient application to vegetables and fruits as well. Following an introduction on the properties of the main edible coating materials, the preparation technologies of ECF with NPs are summarized. The antimicrobial activity of ECF with NPs against the tested microorganism was observed by many researchers. This might be mainly due to the electrostatic interaction between the cationic polymer or free metal ions and the charged cell membrane, the photocatalytic reaction of NPs, the detachment of free metal ion, and partly due to the antimicrobial activity of edible materials. Moreover, their physical, mechanical and releasing properties are discussed in detail, which might be influenced by the concentration of NPs. The preservation potential on the quality of fruits and vegetables indicates that various ECF with NPs might be used as the ideal materials for food application. Following the introduction on these characteristics, an attempt is made to predict future trends in this field.

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«Janus»-like Cu-Fe bimetallic nanoparticles with high antibacterial activity

Cited by 31 publications

References 17 publications

Unveiling the role of novel biogenic functionalized CuFe hybrid nanocomposites in boosting anticancer, antimicrobial and biosorption activities

Unveiling the role of novel biogenic functionalized CuFe hybrid nanocomposites in boosting anticancer, antimicrobial and biosorption activities

Morphology and Antibacterial Properties of Copper Precipitates in Ferrite Stainless Steel

Antimicrobial Nanoparticles Incorporated in Edible Coatings and Films for the Preservation of Fruits and Vegetables

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