James Wardrop and Equine Recurrent Uveitis

Ophthalmic alterations in horses with leptospirosis by serovar Icterohaemorrhagiae in Rio de Janeiro, Brazil

“…In addition, it is noteworthy that a primary lesion of leptospirosis includes damage to the endothelial lining of small blood vessels (Frellstedt 2009). Other indications of uveitis in the posterior segment were also significantly more prevalent in seroreactive horses, including peripapillary focal or alar depigmentation, that resulted in chorioretinal scarring in the nontapetal area of the retina, known as "bullet hole" and "butterfly" lesions respectively (Gilger 2005, Paglia et al 2006.…”

Ophthalmic alterations in horses with leptospirosis by serovar Icterohaemorrhagiae in Rio de Janeiro, Brazil

“…In addition, it is noteworthy that a primary lesion of leptospirosis includes damage to the endothelial lining of small blood vessels (Frellstedt 2009). Other indications of uveitis in the posterior segment were also significantly more prevalent in seroreactive horses, including peripapillary focal or alar depigmentation, that resulted in chorioretinal scarring in the nontapetal area of the retina, known as "bullet hole" and "butterfly" lesions respectively (Gilger 2005, Paglia et al 2006.…”

Infectious Uveitis in Horses and New Insights in Its Leptospiral Biofilm-Related Pathogenesis

“…77, VII) (citation in [104]). The well-known Scottish human surgeon James Wardrop successfully competed for a prize offered by the Board of Agriculture in 1819 for the best "Essay on the diseases of the eye of the horse, and on their treatment" [105,106]. Since the end of the 19th and the beginning of the 20th century, very characteristic descriptions of recurrent uveitis bouts in horses have been published repeatedly, and different infectious causes for this equine ocular disease have been postulated by various authors (numerous citations in [107][108][109][110]).…”

Prognosis and impact of equine recurrent uveitis

“…c Significantly more likely to be blind than horses without cataracts (P<0.001; Pearson's Chi-square). 4 Immature, mature or hypermature cataract. d Significantly more likely to be blind than horses without vitreal inflammation (P<0.0014; Pearson's Chi-square).…”

Ophthalmic alterations in horses with leptospirosis by serovar Icterohaemorrhagiae in Rio de Janeiro, Brazil

“…In addition, it is noteworthy that a primary lesion of leptospirosis includes damage to the endothelial lining of small blood vessels (Frellstedt 2009). Other indications of uveitis in the posterior segment were also significantly more prevalent in seroreactive horses, including peripapillary focal or alar depigmentation, that resulted in chorioretinal scarring in the nontapetal area of the retina, known as "bullet hole" and "butterfly" lesions respectively (Gilger 2005, Paglia et al 2006.…”

Infectious Uveitis in Horses and New Insights in Its Leptospiral Biofilm-Related Pathogenesis

“…77, VII) (citation in [104]). The well-known Scottish human surgeon James Wardrop successfully competed for a prize offered by the Board of Agriculture in 1819 for the best "Essay on the diseases of the eye of the horse, and on their treatment" [105,106]. Since the end of the 19th and the beginning of the 20th century, very characteristic descriptions of recurrent uveitis bouts in horses have been published repeatedly, and different infectious causes for this equine ocular disease have been postulated by various authors (numerous citations in [107][108][109][110]).…”

Prognosis and impact of equine recurrent uveitis

“…c Significantly more likely to be blind than horses without cataracts (P<0.001; Pearson's Chi-square). 4 Immature, mature or hypermature cataract. d Significantly more likely to be blind than horses without vitreal inflammation (P<0.0014; Pearson's Chi-square).…”

Ophthalmic alterations in horses with leptospirosis by serovar Icterohaemorrhagiae in Rio de Janeiro, Brazil

“…In addition, it is noteworthy that a primary lesion of leptospirosis includes damage to the endothelial lining of small blood vessels (Frellstedt 2009). Other indications of uveitis in the posterior segment were also significantly more prevalent in seroreactive horses, including peripapillary focal or alar depigmentation, that resulted in chorioretinal scarring in the nontapetal area of the retina, known as "bullet hole" and "butterfly" lesions respectively (Gilger 2005, Paglia et al 2006.…”

Infectious Uveitis in Horses and New Insights in Its Leptospiral Biofilm-Related Pathogenesis

“…77, VII) (citation in [104]). The well-known Scottish human surgeon James Wardrop successfully competed for a prize offered by the Board of Agriculture in 1819 for the best "Essay on the diseases of the eye of the horse, and on their treatment" [105,106]. Since the end of the 19th and the beginning of the 20th century, very characteristic descriptions of recurrent uveitis bouts in horses have been published repeatedly, and different infectious causes for this equine ocular disease have been postulated by various authors (numerous citations in [107][108][109][110]).…”

Prognosis and impact of equine recurrent uveitis

“…c Significantly more likely to be blind than horses without cataracts (P<0.001; Pearson's Chi-square). 4 Immature, mature or hypermature cataract. d Significantly more likely to be blind than horses without vitreal inflammation (P<0.0014; Pearson's Chi-square).…”