Ivermectin in Elderly Patients

Ivermectin alone or in combination with benzyl benzoate in the treatment of human immunodeficiency virus-associated scabies

“…An increase in the death rate among residents in a long‐term care facility after the use of ivermectin 26 has remained unconfirmed. 27–32 …”

Response to ‘A call to standardize the BCC:SCC ratio’

“…that BCCs are frequently of mixed-tumour categories, with superficial BCC usually found coexisting with other (dermal) subtypes. 5 In terms of the epidemiological utility of the BCC:SCC ratio, we strongly hold that its use is enhanced by the exclusion of SCCis. This is illustrated in organ transplant recipients where a marked reversal of the ratio enables us to appreciate the high morbidity and mortality that occurs as a consequence, 6 and thus to deploy appropriate service provision to detect and treat invasive SCC early.…”

“…We, and others, have highlighted the deficiencies in this report, and have called for an editorial warning to be placed on the article. 3,5 The data concerning all-cause mortality in the cohort studied by Bernigaud et al in the 56 days after the administration of ivermectin would be extremely useful for those involved in the research and management of scabies outbreaks. We believe this is the first published use of ivermectin as a first-line agent for the control of scabies in an LTCF for the elderly.…”

Clinical diagnosis and treatment of scabies, a neglected tropical disease

“…Oral ivermectin, a macrocyclic lactone structurally similar to the macrolide antibiotics but devoid of antibacterial activity, has a good safety profile 19,20 and has revolutionised treatment of ectoparasites. 21,22 The efficacy of oral ivermectin https://www.safpj.co.za Open Access is equivalent to or better than that of topically applied lindane 23 and benzyl benzoate. 24 In one study, two doses of ivermectin were found to be as effective as a single application of permethrin.…”