It's Not over When it's Over: Long-Term Symptoms in Cancer Survivors—A Systematic Review

Harrington, Cherise B.; Hansen, Jennifer A.; Moskowitz, Michal C.; Todd, Briana L.; Feuerstein, Michael

doi:10.2190/pm.40.2.c

Cited by 562 publications

(431 citation statements)

References 100 publications

Supporting

Mentioning

390

Contrasting

Unclassified

Order By: Relevance

“…The literature provides evidence that being a cancer survivor very often means having to face late-presenting and/or long-term effects, both psychosocial and physical, that can impact different QoL domains years after treatment ends. Musculoskeletal problems, pain, sexual dysfunction, fatigue, anxiety, depressive symptoms, and cognitive limitations are some of the effects which can be found during treatment, and which can also affect long-term cancer survivorship [3][4][5][6]. More specific long-term effects such as relapses, iatrogenic tumors, fear of cancer recurrence, and limitations in restarting one's pre-illness functioning, are frequently denounced by survivors [3][4][5].…”

Section: Introductionmentioning

confidence: 99%

Long-term quality of life profile in oncology: a comparison between cancer survivors and the general population

Annunziata

Muzzatti

Flaiban

et al. 2017

Support Care Cancer

View full text Add to dashboard Cite

Purpose Understanding the quality of life (QoL) of cancer survivors is relevant to both clinical practice and health care policy. The current study compared the QoL profile in this specific population with that of a normative sample for the general population, as well as with those of both healthy and oncological patients normative sub-samples. In addition, associations between the obtained QoL profile and the main socio-demographic and clinical characteristics of the sample were examined. Methods Three hundred and ninety-two adult long-term cancer survivors (i.e., people 5 + years from their cancer diagnosis who were free from it and its treatments) were enrolled during follow-up visits and compiled the Short Form 36 Health Survey. Results In comparison with the normative data for the adult general population, the present sample showed lower scores in Physical functioning, Role-physical limitation, and Roleemotional limitations (all differences were both statistically and clinically significant); the difference in Vitality was only statistically significant. In all eight SF-36 scales, scores of the present sample were clinically and statistically lower than those of the normative healthy subsample, whereas they were statistically and clinically higher than those of normative subsample which had experienced cancer, except for Rolephysical limitation. The QoL profile was associated with gender (p = 0.002), age (p = 0.001), education (p < 0.001), occupational status (p < 0.001), and the presence of other health issues (p < 0.001). Conclusion These data support the utility of rehabilitative programs which integrate both healthcare and social interventions. In addition, they encourage the monitoring of the health status of this specific population, within a broad frame which simultaneously takes into consideration health and QoL.

show abstract

Section: Introductionmentioning

confidence: 99%

Long-term quality of life profile in oncology: a comparison between cancer survivors and the general population

Annunziata

Muzzatti

Flaiban

et al. 2017

Support Care Cancer

View full text Add to dashboard Cite

show abstract

“…Because of the direct and long-term effects of cancer and its treatment, most survivors do not return to their previous state of well-being [4,5]. Cancer survivors suffer from a range of problems, varying from fatigue, reduced physical fitness, and psychological problems to symptoms related to specific cancer types, such as lymphedema or difficulties with speaking and swallowing after head and neck surgery [6].…”

Section: Introductionmentioning

confidence: 99%

Effectiveness of Multidimensional Cancer Survivor Rehabilitation and Cost-Effectiveness of Cancer Rehabilitation in General: A Systematic Review

et al. 2012

View full text Add to dashboard Cite

Introduction. Many cancer survivors suffer from a combination of disease-and treatment-related morbidities and complaints after primary treatment. There is a growing evidence base for the effectiveness of monodimensional rehabilitation interventions; in practice, however, patients often participate in multidimensional programs. This study systematically reviews evidence regarding effectiveness of multidimensional rehabilitation programs for cancer survivors and cost-effectiveness of cancer rehabilitation in general.Methods. The published literature was systematically reviewed. Data were extracted using standardized forms and were summarized narratively.Results. Sixteen effectiveness and six cost-effectiveness studies were included. Multidimensional rehabilitation programs were found to be effective, but not more effective than monodimensional interventions, and not on all outcome measures. Effect sizes for quality of life were in the

show abstract

“…For example, the WHOQOL-BREF (2004b) measures physical health, psychological health, self-esteem, sexual health, social relationships and environment. Cancer survivors generally report lower QOL scores than matched individuals without cancer (Baker et al, 2003(Baker et al, , 2009Lazovich et al, 2009) and poor quality of life can be long-lasting, since it has been shown that cancer survivors can experience physical and psychological symptoms for more than ten years following their treatment (Harrington et al, 2010). Research therefore has sought, and continues to seek, ways in which quality of life might be improved in this population group.…”

Section: Quality Of Lifementioning

confidence: 99%

Physical Activity and Cancer

Bk¹,

Ih²,

Rohde³

2013

Encyclopedia of Behavioral Medicine

View full text Add to dashboard Cite

It is widely accepted that physical activity is important for physical functioning and well-being, and as such the promotion of active lifestyles is becoming increasingly significant in public health policy both in the UK and worldwide. Sedentary lifestyles have been associated with increased risk of obesity and preventable disease including diabetes, coronary heart disease and some cancers. With regards cancer specifically, this chapter will provide a brief overview on current opinions on the link between physical activity and cancer prevention.The published evidence focuses both on primary and secondary prevention. More recent evidence has investigated the use of physical activity in secondary prevention for those who have been diagnosed with cancer and proposed a link between physical activity, morbidity and mortality in those with cancer. The evidence-base for secondary prevention is more limited. Nevertheless, studies to date have indicated that physical activity can improve both physical functioning and psychological outcomes in cancer survivors, and significantly improve quality of life.The exact nature of those interventions which confer the most positive effects is less well-established, and there is a current lack of consensus on the most appropriate type, intensity and duration of activity for people with cancer. It has not yet been wellestablished as to which stage of the treatment programme physical activity should be encouraged (during or following treatment) or the most appropriate length of time during which structured physical activity interventions should be delivered to achieve beneficial results.These factors will be discussed in this chapter, and barriers to engaging in physical activity for those with a diagnosis of cancer will be considered. The chapter will conclude with a summary of key findings and the potential for further research.

show abstract

It's Not over When it's Over: Long-Term Symptoms in Cancer Survivors—A Systematic Review

Cited by 562 publications

References 100 publications

Long-term quality of life profile in oncology: a comparison between cancer survivors and the general population

Long-term quality of life profile in oncology: a comparison between cancer survivors and the general population

Effectiveness of Multidimensional Cancer Survivor Rehabilitation and Cost-Effectiveness of Cancer Rehabilitation in General: A Systematic Review

Physical Activity and Cancer

Contact Info

Product

Resources

About