Isotretinoin treatment of human immunodeficiency virus-associated eosinophilic folliculitis. Results of an open, pilot trial

Otley, C. C.

doi:10.1001/archderm.131.9.1047

Cited by 12 publications

(10 citation statements)

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“…This is further supported by good response to 3 weeks of systemic metronidazole 14 . Others proposed that HIV-EF is a follicular hypersensitivity reaction to an undetermined target antigen 15 . The presence of many degranulated eosinophils and mast cells in the skin biopsies suggests that these cells may play a role in the pathogenesis.…”

Section: Discussionmentioning

confidence: 99%

“…It produced symptomatic relief in 2 weeks' time. The proposed mechanism is due to inhibition of neutrophil chemotaxis, inhibition of lysosomal enzyme release by neutrophils and in¯uence of oxygen products 15 . One report suggested that isotretinoin should be the ® rst-line treatment of eosinophilic pustular folliculitis when the seboglandular unit was primarily involved 17 .…”

Section: Discussionmentioning

confidence: 99%

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HIV associated eosinophilic folliculitis in a Chinese woman: a case report and a survey in Hong Kong

Chong²,

Ho³

1998

Int J STD AIDS

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This is the first survey of eosinophilic folliculitis (EF) in patients infected with the human immunodeficiency virus (HIV) in Hong Kong. The present report provides the local data on HIV-associated eosinophilic folliculitis (HIV-EF) and includes the first Chinese, heterosexual female patient with this condition. This is a retrospective study on all HIV-positive patients (n = 451) attending the outpatient clinic of the AIDS Unit in Hong Kong. Patients diagnosed as having EF with histological support were included for analysis. The data were presented by descriptive method. Three patients were identified, all of them had skin biopsies done which confirmed the diagnosis; including the female case. Recognition of HIV-EF is important because it is indicative of significant immunosuppression with risk of opportunistic infection. We concluded that HIV-EF is no longer an exclusive male disease in homosexual patients only. We expect more female patients or heterosexual subjects who are HIV positive developing this disease in the future.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

HIV associated eosinophilic folliculitis in a Chinese woman: a case report and a survey in Hong Kong

Chong²,

Ho³

1998

Int J STD AIDS

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“…19 In contrast, suppurative folliculitis typically demonstrates microorganisms surrounded by neutrophils and macrophages, along with frequent follicular rupture. In a study of 52 skin biopsy specimens, McCalmont et al 20 were able to distinguish HIV-EF from other folliculitides based on the above histopathologic findings.…”

Section: Commentmentioning

confidence: 99%

Eosinophilic Folliculitis in 2 HIV-Positive Women

Hayes¹,

Hille²,

Goldberg³

2004

Arch Dermatol

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“…Four of seven patients experienced lasting remission from one course of therapy, while three others suffered brief relapses, necessitating one to three further courses of isotretinoin therapy. Side effects were tolerable, and no apparent adverse effects on patients' immune status were noted [99].…”

Section: Aids-associated Eosinophilic Folliculitismentioning

confidence: 92%