1985
DOI: 10.1001/archderm.121.3.308b
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Isotretinoin therapy for progressive systemic sclerosis

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Cited by 9 publications

(6 citation statements)
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“…ATRA has been reported to control and modulate the autoimmune diseases and has a clinically significant therapeutic effect on SSc [ 20 , 21 ]. In this study, we treated SSc CD4+ T cells with or without TGF- β and/or ATRA in vitro .…”
Section: Discussion
mentioning
confidence: 99%
“…Retinoic acids (RA) have been reported to induce clinically significant therapeutic effects on SSc [ 20 , 21 ]. However, the underlying molecular mechanism of RA in the prevention of SSc remains unclear.…”
Section: Introduction
mentioning
confidence: 99%
See 1 more Smart Citation
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
“…ATRA has been reported to control and modulate the autoimmune diseases and has a clinically significant therapeutic effect on SSc [ 20 , 21 ]. In this study, we treated SSc CD4+ T cells with or without TGF- β and/or ATRA in vitro .…”
Section: Discussion
mentioning
confidence: 99%
“…Retinoic acids (RA) have been reported to induce clinically significant therapeutic effects on SSc [ 20 , 21 ]. However, the underlying molecular mechanism of RA in the prevention of SSc remains unclear.…”
Section: Introduction
mentioning
confidence: 99%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
“…The usefulness of retinoids (retinoic acid) in treating skin sclerosis of systemic scleroderma has been reported in the literature [ 1 , 2 , 7 ]. Retinoids decrease collagen synthesis [ 8 ].…”
Section: Discussion
mentioning
confidence: 99%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
“…Systemic or topical retinoids have been reported to be a successful treatment for skin sclerosis due to systemic sclerosis. 10,11 It was suggested that oral etretinate treatment may be a plausible new therapy for sclerodermatous chronic graft-versus-host disease. 12 Our results were thought to support this trend.…”
Section: Discussion
mentioning
confidence: 99%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.