Isolation, structure and bioactivities of the polysaccharides from Angelica sinensis (Oliv.) Diels: A review

Characterization and comparison of polysaccharides from Lycium barbarum in China using saccharide mapping based on PACE and HPTLC

“…mongholicus. Previous studies have shown that pectin-like polysaccharides exist in L. barbarum (Amagase and Farnsworth, 2011), P. notoginseng , A. sinensis (Jin, Zhao, Huang, Xu, & Shang, 2012), and A. membranaceus (Jin, Zhao, Huang, & Shang, 2014). Therefore, the PACE fingerprint of pectinase digested polysaccharides from L. barbarum was used to discriminate polysaccharides from P. notoginseng, A. sinensis, and A. membranaceus var.…”

Study to establish the role of JAK2 and SMAD1/5/8 pathways in the inhibition of hepcidin by polysaccharides from Angelica sinensis

“…Diels, a well-known Chinese herbal medicine, have been used for thousands of years as a hematopoietic, tonic and anti-inflammatory agent for the treatment of menstrual disorders, dysmenorrheal and amenorrhea (Jin et al, 2012). As one of the active components, Angelica sinensis polysaccharide (ASP) has various bioactivities, such as hematopoiesis (Lee et al, 2012), immunomodulation (Liu et al, 2010a), radioprotection (Jin et al, 2012), and anti-tumor activity (Cao et al, 2010). Liu et al (2010b) found that ASP is the major component responsible for the hematopoietic effect of Angelica sinensis (AS).…”

A novel and rapid HPGPC-based strategy for quality control of saccharide-dominant herbal materials: Dendrobium officinale, a case study

“…Generally, isolation and purification followed by complete structural characterization, namely homogeneity and molecular weight determination, compositional monosaccharide analysis, glucosidic linkage type confirmation, and then repetitive structural unit speculation, is the most reliable approach to quality evaluation of polysaccharides and oligosaccharides in herbal materials [2]. However, it is widely acknowledged that the methodologies involved are extremely complicated, difficult, and time-consuming [3][4][5][6] and therefore not suitable for routine analysis. In addition to the comprehensive approach described above, there are two kinds of analytical methods, namely, total sugar content Electronic supplementary material The online version of this article (doi:10.1007/s00216-014-8060-9) contains supplementary material, which is available to authorized users.…”