Isolation of Bacteria and Histomorphology of Turkey Liver Granulomas

Ka, Langheinrich; Schwab, Brian

doi:10.2307/1588761

Cited by 11 publications

(6 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Liver granulomas examined in this study were similar grossly and microscopically to those reported previously [7,8]. The cellular composition of late granulomas indicates a chronic, healing stage of the lesions.…”

Section: Discussionsupporting

confidence: 86%

“…Some species of Staphylococcus are known for their capacity to produce granulomas in poultry [9], but no cocci were seen in lesions of this study. Staphylococci also were isolated from some turkey-liver granulomas in previous studies [7,8]. Experimental work has indicated that infection of the liver by the filamentous bacillus is dependent on primary damage to the intestinal wall [8].…”

Section: Discussionmentioning

confidence: 99%

“…Granulomas are a common cause of condemnation of turkey livers at slaughter [5,7,8]. Affected livers contain multiple, firm, pale-yellow, spherical masses I to 3 mm in diameter.…”

mentioning

confidence: 99%

“…Both anaerobic and aerobic bacteria have been isolated from the granulomas [7,8]. Granulomas were produced in livers of turkeys inoculated intravenously with an anaerobic, filamentous bacillus and in turkeys inoculated orally with the filamentous bacillus and a virulent strain of Streptococcus faecalis subsp.…”

mentioning

confidence: 99%

See 3 more Smart Citations

Pathology of Liver Granulomas in Turkeys

1983

View full text Add to dashboard Cite

Abstract. Liver granulomas from five-and seven-week-old turkeys were studied by light and electron microscopy and by bacterial culture. Granulomas of five-week-old poults were composed of a caseous, necrotic center surrounded by consecutive zones of heterophils, giant cells, macrophages, and finally by lymphocytes. Tissue Gram and modified Dieterle stains demonstrated numerous gram-positive, filamentous bacteria in necrotic centers with radial extension of the bacteria to the zone of giant cells. Electron microscopic examination revealed septate, filamentous bacteria within an electron-dense milieu between heterophils, macrophages, and giant cells.An anaerobic, gram-positive bacillus and a staphylococcus were isolated from most granulomas examined. In broth, the bacillus formed long filaments or chains morphologically similar to those in tissue sections. The bacillus was identified tentatively as Eubacterium tortuosum. The staphylococcus had cultural reactions typical for Staphylococcus epidermidis. Intravenous inoculation of three-week-old poults with a mixture of E. tortuosum and S. epidermidis produced granulomas in liver and spleen and multiple mucosal ulcers in the duodenum and colon.

show abstract

Section: Discussionsupporting

confidence: 86%

Section: Discussionmentioning

confidence: 99%

“…Granulomas are a common cause of condemnation of turkey livers at slaughter [5,7,8]. Affected livers contain multiple, firm, pale-yellow, spherical masses I to 3 mm in diameter.…”

mentioning

confidence: 99%

mentioning

confidence: 99%

See 2 more Smart Citations

Pathology of Liver Granulomas in Turkeys

1983

View full text Add to dashboard Cite

show abstract

“…The topological position within the liver sinusoid makes the Kupffer cells the first macrophages to come into contact with foreign or noxious material including viruses, bacteria, unicellular eukaryotes and their products that enter the circulation by the way of the portal vein (15). Together with dendritic cells (65), liver sinusoidal endothelial cells (53), stellate cells (52) isolated and identified from splenic and hepatic granulomas of slaughtered chickens and turkeys (20,31). Experimental Eubacterium infection in turkeys and chickens by intravenous inoculation, facilitated induction of hepatic and splenic granulomas similar as in the natural disease (4,20).…”

Section: Introductionmentioning

confidence: 99%