Isolation and characterization of antioxidant and antimicrobial compounds from Anacardium occidentale L. (Anacardiaceae) leaf extract

Ajileye, O. O.; Obuotor, Efere Martins; Akinkunmi, Ezekiel Olugbenga; Aderogba, M.A.

doi:10.1016/j.jksus.2014.12.004

Cited by 76 publications

(63 citation statements)

References 30 publications

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“…Quercetin-3-O-rhamnoside, isolated from the ethyl acetate fraction of Anacardium occidentale L. leaves, also revealed a good antimicrobial activity against all studied strains (Escherichia coli ATCC 25922, Pseudomonas aeruginosa ATCC 27853, P. fluorescence NCIB 3756, Staphylococcus aureus ATCC 29213, Bacillus subtilis NCIB 3610, Klebsiella pneumonia (clinical strain) and Clostridium sporogens NCIB 532). 39 The combination between two isolated compounds, quercetin-3-O-rutinoside and quercetin-3-O-rhamnoside, also revealed a higher antimicrobial activity than all extracts, which confirms GI 50 values (mean ± SD) correspond to the sample concentration achieving 50% of growth inhibition in human tumor cell lines or in liver primary culture PLP2. In each row, different letters mean significant differences between M. nivelii extract and fractions (p < 0.05).…”

Section: Antibacterial Activitysupporting

confidence: 53%

“…the synergistic effect of these two compounds. 39 Ellagitannins have been also reported to present high antimicrobial activity, 40 which can explain the high antibacterial potential of the herein studied samples. Overall, the differences found in the bioactive properties of the aqueous extract and the organic fractions can be related to the different profiles and quantities of phenolic compounds present in each sample.…”

Section: Antibacterial Activitymentioning

confidence: 61%

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Detailed phytochemical characterization and bioactive properties of Myrtus nivelii Batt & Trab

et al. 2017

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The endemic Algerian myrtle, Myrtus nivelii Batt & Trab., was evaluated for its bioactive properties, such as antioxidant, anti-inflammatory, cytotoxic and antibacterial activities, and correlated with the individual phenolic compounds identified in its crude aqueous extract and subsequent organic fractions (ethyl acetate and butanol). Flavonols, such as myricetin, kaempferol and quercetin glycoside derivatives, were the major phenolic compounds found, along with the presence of ellagitannins. The ethyl acetate fraction contained the highest amount of phenolic compounds, followed by the butanol fraction and, finally, the crude aqueous extract. In general, all samples exhibited an excellent bioactivity, namely the ethyl acetate fraction that presented strong antioxidant activity, when compared to the standard trolox, strong cytotoxicity and antibacterial activity, especially against MRSA and MSSA. The present study revealed that the ethyl acetate fraction of M. nivelii could be used as a source of bioactive compounds in the food and pharmaceutical industries.

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Section: Antibacterial Activitysupporting

confidence: 53%

Section: Antibacterial Activitymentioning

confidence: 61%

Detailed phytochemical characterization and bioactive properties of Myrtus nivelii Batt & Trab

et al. 2017

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“…The antioxidant power of the leaves (TAC) was measured through the FRAP technique (phosphomolybdenum and ferric reducing antioxidant power techniques). The microbicide test with bacteria and fungi showed little effectiveness against bacteria activity and no effectiveness against fungi, with better results for gram-negative bacteria [23]. Cashew nut bran was also evaluated in different stages, raw and cooked, by Soares et al [31], using DPPH and ABTS.…”

Section: Resultsmentioning

confidence: 99%

Antioxidant and Antimicrobial Activities of Crude Extracts and Fractions of Cashew (Anacardium occidentale L.), Cajui (Anacardium microcarpum), and Pequi (Caryocar brasiliense C.): A Systematic Review

Baptista

Gonçalves

Bressan

et al. 2018

Oxidative Medicine and Cellular Longevity

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The accentuated increase in the use of medicinal plants by the population to treat diseases makes it necessary to carry out pharmacological studies in order to contribute to the scientific knowledge and clarify the mechanisms involved in the main compounds present in these plants. Due to the difficulty of combating antimicrobial-resistant microorganisms, plants become a low-cost and effective alternative. The stem, fruit, and leaves of plants are used to measure antioxidant and antimicrobial capacity and to combat the oxidative degradation of free radicals produced in the presence of xenobiotics. A systematic review is a powerful tool that incorporates the variability among the studies, providing an overall estimate of the use of plant extracts as antioxidants and antimicrobial activities. In view of the controversies in the literature regarding the use of compounds from plants or the isolation and purification of the main substances for the prevention of bacterial various therapeutic actions, the aim of this was to present a systematic review on the antimicrobial and antioxidant properties of cashew (Anacardium occidentale), cajui (Anacardium microcarpum), and pequi (Caryocar brasiliense). The following databases were analyzed: PubMed/Medline, Virtual Health Library (LILACS and SciELO), and Science Direct. Out of 425 articles, 33 articles have been used in this study, which were also represented in the Prisma Statement. In vitro antioxidant tests were conducted in 28 studies using different methodologies. Most of the tests involving the studied species demonstrated positive antioxidant potential and antimicrobial properties. The results provide important data and perspectives into the use of natural products that can contribute to the treatment of various diseases.

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“…On accepting a proton from a donor (an antioxidant), the DPPH loses the free radical nature and gets converted into a corresponding yellow colored hydrazine i.e., DPPHH and the extent of bleaching of purple color depends on proton donating ability of sample. The assay has been employed by various researchers to evaluate radical scavenging potential of various kinds of samples including plant extracts and plant metabolites [24,33,53,[56][57][58][59][60][61][62][63]. In this study, we evaluated the potential of leaf and fruit extract of G. gummifera by DPPH assay and the result is shown in fig.…”

Section: Antibacterial Activity Of Leaf and Fruit Extract Of G Gummimentioning

confidence: 99%

Antimicrobial, Antiradical and Insecticidal Activity of Gardenia Gummifera L. F. (Rubiaceae)

Kekuda¹,

Raghavendra

Shilpa³

et al. 2017

Int J Pharm Pharm Sci

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Objective: The present study was carried out to investigate antimicrobial, antiradical and insecticidal potential of leaf and fruit of Gardenia gummifera L. f. (Rubiaceae). Methods:The leaf and fruits were shade dried, powdered and extracted by maceration process using methanol. Antibacterial activity was evaluated against Gram positive and Gram negative bacteria by Agar well diffusion assay. Antifungal activity was determined against six seed-borne fungi by Poisoned food technique. Antiradical activity of leaf and fruit extracts was evaluated by 1,1-diphenyl-2-picrylhydrazyl (DPPH) and 2,2-azinobis 3-ethylbenzothiazoline 6-sulfonate (ABTS) radical scavenging assays. Insecticidal activity of leaf and fruit extracts, in terms of larvicidal and pupicidal activity, was assessed against larvae and pupae of Aedes aegypti. Results:Both the extracts inhibited all test bacteria. Marked antibacterial activity was displayed by fruit extract when compared to leaf extract. S. epidermidis and E. coli were inhibited to highest and least extent by both extracts respectively. Fruit extract was found to exhibit higher antifungal effect when compared to leaf extract. Leaf extract and fruit extract exhibited highest inhibitory activity against A. niger and A. flavus respectively. Leaf and fruit extracts scavenged DPPH radical's dose dependently with an IC50 value of 49.01µg/ml and 2.53µg/ml respectively. The scavenging of ABTS by leaf and fruit extracts was dose dependent and the IC50 Conclusion: Overall, fruit extract of G. gummifera exhibited marked antimicrobial, antiradical and insecticidal activity when compared to leaf extract. The plant can be used for developing agents/formulations effective against infectious microorganisms, oxidative stress and insect vectors that transmit dreadful diseases. The observed bioactivities could be ascribed to the presence of active principles which are to be isolated and characterized.value for leaf and fruit extract was 2.58µg/ml and 2.31µg/ml respectively. Fruit extract was shown to exhibit marked antiradical activity when compared to leaf extract. Leaf and fruit extracts exhibited dose dependent insecticidal activity in terms of larvicidal and pupicidal activity and the susceptibility of larvae and pupae to extracts was in the order II instar larvae>IV instar larvae>pupae. Fruit extract displayed marked insecticidal potential when compared to leaf extract.

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Isolation and characterization of antioxidant and antimicrobial compounds from Anacardium occidentale L. (Anacardiaceae) leaf extract

Cited by 76 publications

References 30 publications

Detailed phytochemical characterization and bioactive properties of Myrtus nivelii Batt & Trab

Detailed phytochemical characterization and bioactive properties of Myrtus nivelii Batt & Trab

Antioxidant and Antimicrobial Activities of Crude Extracts and Fractions of Cashew (Anacardium occidentale L.), Cajui (Anacardium microcarpum), and Pequi (Caryocar brasiliense C.): A Systematic Review

Antimicrobial, Antiradical and Insecticidal Activity of Gardenia Gummifera L. F. (Rubiaceae)

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