Isolated Lichen Planus of Lower Lip: A Case Report

Samal, Dillip Kumar; Behera, Geeta; Gupta, Vikas; Majumdar, Kaushik; Khurana, Ujjawal

doi:10.1007/s12070-014-0768-5

Cited by 7 publications

(15 citation statements)

References 7 publications

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“…All clinical variants of oral lichen planus that have been described in the literature may also be identified in the isolated form of the lips which are: reticular, papular, erosive, bullous and atrophic form [1,3].…”

Section: Discussionmentioning

confidence: 99%

“…In addition, we revealed hypergranulosis, edema and a dense band like lymphocytic infiltrate in the dermal-epidermal interface. Colloid bodies representing necrotic keratinocytes known as Civatte bodies are also identified [1,3,5,6].…”

Section: Discussionmentioning

confidence: 99%

“…Oral lichen planus is a benign dermatosis, nevertheless, some cases of transformation of lichen planus of the lips into squamous cell carcinoma were documented [2][3][4].…”

Section: Discussionmentioning

confidence: 99%

“…Usually, isolated lip lichen planus shows a great remission with topical treatment, most commonly with topical corticosteroids. Systemic and intralesional administration are rarely used [2][3][4]. Topical steroids such as Clobetasol propionate, Fluticasone propionate are the first line treatment [3].…”

Section: Discussionmentioning

confidence: 99%

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Isolated lichen planus of the lips: cases reports and literature review

Garma

Hasni

Annabi

et al. 2020

J Oral Med Oral Surg

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Introduction: Lichen planus is an inflammatory mucocutaneous dermatosis involving skin, appendages and mucosa. Oral mucosa is the most commonly involved in all its sites, rarely the lips especially when isolated. The aim was to conduct a literature review about isolated lichen planus of the lips and reporting two case reports of this lesion in order to highlight epidemiologic, clinical and histological features and therapeutic modalities of this lesion. Observations: Case report 1: a 34-year-old diabetic male patient consulted for an erosive, crusted and hemorrhagic cheilitis of the lower lip. Clinical and histological examination led to the diagnosis of isolated lichen planus of the lips. Case report 2: a 33-year-old female patient was referred from dermatology department for biopsy of chronic cheilitis of the lower lip. Clinical and histological examination confirmed the diagnosis of isolated lichen planus of the lips. Discussion: The review based on 34 case reports of isolated lichen planus of the lips, in addition to literature data confirmed that it is a benign rare lesion affecting mostly male patients having middle age with preponderance of the lower lip, its erosive form is the most frequent and it presents a favorable healing with topical treatment particularly corticosteroids.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

“…Oral lichen planus is a benign dermatosis, nevertheless, some cases of transformation of lichen planus of the lips into squamous cell carcinoma were documented [2][3][4].…”

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Isolated lichen planus of the lips: cases reports and literature review

Garma

Hasni

Annabi

et al. 2020

J Oral Med Oral Surg

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“…Surgical excision of OLP is indicated as an alternative treatment for isolated plaques or nonhealing erosions (Samal, Behera, Gupta, Majumdar, & Khurana, 2014;Yang et al, 2016). The preferred method for restoration of the vermilion is anterior advancement of the mucosa (Baker & Swanson, 1995).…”

Section: Present Of Volkmann's Cheilitis With Inflammatory Change Loomentioning

confidence: 99%

Surgical excision and mucosal advancement flap: Treatment for refractory lichen planus of the lip

Kim

Lim

et al. 2018

Dermatologic Therapy

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Lichen planus of the lip (LPL) is not common, and only a few cases have been reported. Medical treatment modalities for LPL are not always effective. Therefore, treatment of this presentation is difficult and challenging. A 41-year-old man was referred to the dermatology clinic with a chronic, painful erosion on the lower lip and buccal mucosa. Treatment with topical steroids, systemic cyclosporine, dapsone, and systemic steroids failed. We performed surgical excision and mucosal advancement flap treatment, with complete response noted after 6 months. Surgical excision with mucosal advancement flap treatment may be effective for the treatment of refractory LPL.

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High-level laser therapy versus scalpel surgery in the treatment of oral lichen planus: a randomized control trial

et al. 2021

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Objective To compare the clinical effectiveness of various types of high-level laser therapy (HLLT) toward scalpel excision for the surgical treatment of erosive oral lichen planus (OLP). Materials and methods The total number of 128 individuals were enrolled in the study. The 35 did not meet the inclusion criteria due to malignancy signs and presence of diabetes mellitus. In total, 8 were lost to follow-up, and 10 were excluded from the analysis, due to analgesics intake. This way 75 patients with the erosive form of OLP were analyzed in three intervention groups (Er:YAG, n = 19; Nd:YAG, n = 15; Er:YAG + Nd:YAG combination, n = 20) and one control group with scalpel excision (n = 21). The therapy effectiveness has been assessed based on the comparison of salivary interleukin (IL)-1β, IL-6 and interferon (IFN)-γ preoperative levels to 14, 30 days, and 2 years postoperation, as well as pain level and time of epithelization. Results All HLLT groups demonstrated a significantly (p > 0.05) higher IL-1β, IL-6, IFNγ and pain level reduction and quicker epithelization toward the control group on the 30th day, except Nd:YAG in case of IFNγ level. The highest IL-1β, IFNγ and pain level reduction and quicker epithelization on the 30th day was observed in Er:YAG group, followed by Er:YAG + Nd:YAG combination, Nd:YAG respectively. However no significant difference was observed between the HLLT groups with regard to IL-6 level reduction. After a 2-year follow-up, no significant difference was observed between all study groups with regard to all variables. Conclusion HLLT yields a superior clinical outcome compared to the scalpel excision for the surgical treatment of oral lichen planus, whereby the Er:YAG has been proposed as the most effective laser type at the end of the first postoperative month. Clinical relevance For the surgical treatment of erosive OLP the Er:YAG laser may be a preferable treatment option compared to Nd:YAG and scalpel surgery. Trial registration The present trial was registered retrospectively in the German Clinical Trials Register, as a member of WHO international clinical trials registry platform, on the 18.03.2020 with the following number: DRKS00020986

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Isolated Lichen Planus of Lower Lip: A Case Report

Cited by 7 publications

References 7 publications

Isolated lichen planus of the lips: cases reports and literature review

Isolated lichen planus of the lips: cases reports and literature review

Surgical excision and mucosal advancement flap: Treatment for refractory lichen planus of the lip

High-level laser therapy versus scalpel surgery in the treatment of oral lichen planus: a randomized control trial

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