Is the Risk of Incidence or Progression of Age-Related Macular Degeneration Increased After Cataract Surgery?

Association between Cataract Surgery and Age-Related Macular Degeneration: A Systematic Review and Meta-Analysis

“…Our findings suggest that studies with primarily clinic-based patient samples have not found an association between cataract surgery and the incidence of late AMD. The possible reasons for the inconsistent findings could be differences in comorbidity distributions between clinic-based patients and population-based controls [ 7 , 16 ]. Of note, the proportion of clinic-based patients with systemic comorbidities was higher than that of the healthy general population living in the community [ 40 , 41 ].…”

“…Clarifying whether there are different risks between types of AMD after cataract surgery is very important from an informed consent perspective. However, the potential for cataract surgery to increase the risk of developing AMD is a long-standing clinical question, [ 7 , 8 ] and the findings from epidemiological studies regarding these associations have been inconsistent [ 8 – 19 ]. Since then, several other studies investigating cataract surgery for AMD have been published [ 17 , 20 , 21 ].…”

Association between Cataract Surgery and Age-Related Macular Degeneration: A Systematic Review and Meta-Analysis

“…Our findings suggest that studies with primarily clinic-based patient samples have not found an association between cataract surgery and the incidence of late AMD. The possible reasons for the inconsistent findings could be differences in comorbidity distributions between clinic-based patients and population-based controls [ 7 , 16 ]. Of note, the proportion of clinic-based patients with systemic comorbidities was higher than that of the healthy general population living in the community [ 40 , 41 ].…”

“…Clarifying whether there are different risks between types of AMD after cataract surgery is very important from an informed consent perspective. However, the potential for cataract surgery to increase the risk of developing AMD is a long-standing clinical question, [ 7 , 8 ] and the findings from epidemiological studies regarding these associations have been inconsistent [ 8 – 19 ]. Since then, several other studies investigating cataract surgery for AMD have been published [ 17 , 20 , 21 ].…”

The Impact of Cataract Surgery on AMD Development and Progression

“……”

Potential guidelines for cataract surgery and rehabilitation in visually impaired patients: Literature analysis

“…Regarding the potential for exacerbating retinal pathology following cataract surgery, it is important to note that epidemiological studies conducted prior to the introduction of anti-VEGF therapy demonstrated an increased risk of both exudative and atrophic forms of AMD, including heightened incidence and progression post-surgery (Figure 1A,B). [38][39][40][41] Currently, there is no conclusive evidence indicating that cataract surgery increases the incidence or progression of AMD, nor does it facilitate the transition from atrophic to neovascular forms of the disease. [42][43][44] The retinal condition should be carefully assessed before surgery, ensuring that the macula is stable, whether in an atrophic or exudative state, before scheduling the procedure.…”

“…Regarding the potential for exacerbating retinal pathology following cataract surgery, it is important to note that epidemiological studies conducted prior to the introduction of anti‐VEGF therapy demonstrated an increased risk of both exudative and atrophic forms of AMD, including heightened incidence and progression post‐surgery (Figure 1A,B ). 38 , 39 , 40 , 41 …”

Association between Cataract Surgery and Age-Related Macular Degeneration: A Systematic Review and Meta-Analysis

“…Our findings suggest that studies with primarily clinic-based patient samples have not found an association between cataract surgery and the incidence of late AMD. The possible reasons for the inconsistent findings could be differences in comorbidity distributions between clinic-based patients and population-based controls [ 7 , 16 ]. Of note, the proportion of clinic-based patients with systemic comorbidities was higher than that of the healthy general population living in the community [ 40 , 41 ].…”

“…Clarifying whether there are different risks between types of AMD after cataract surgery is very important from an informed consent perspective. However, the potential for cataract surgery to increase the risk of developing AMD is a long-standing clinical question, [ 7 , 8 ] and the findings from epidemiological studies regarding these associations have been inconsistent [ 8 – 19 ]. Since then, several other studies investigating cataract surgery for AMD have been published [ 17 , 20 , 21 ].…”

The Impact of Cataract Surgery on AMD Development and Progression

“……”

Potential guidelines for cataract surgery and rehabilitation in visually impaired patients: Literature analysis

“…Regarding the potential for exacerbating retinal pathology following cataract surgery, it is important to note that epidemiological studies conducted prior to the introduction of anti-VEGF therapy demonstrated an increased risk of both exudative and atrophic forms of AMD, including heightened incidence and progression post-surgery (Figure 1A,B). [38][39][40][41] Currently, there is no conclusive evidence indicating that cataract surgery increases the incidence or progression of AMD, nor does it facilitate the transition from atrophic to neovascular forms of the disease. [42][43][44] The retinal condition should be carefully assessed before surgery, ensuring that the macula is stable, whether in an atrophic or exudative state, before scheduling the procedure.…”

“…Regarding the potential for exacerbating retinal pathology following cataract surgery, it is important to note that epidemiological studies conducted prior to the introduction of anti‐VEGF therapy demonstrated an increased risk of both exudative and atrophic forms of AMD, including heightened incidence and progression post‐surgery (Figure 1A,B ). 38 , 39 , 40 , 41 …”

Association between Cataract Surgery and Age-Related Macular Degeneration: A Systematic Review and Meta-Analysis

“…Our findings suggest that studies with primarily clinic-based patient samples have not found an association between cataract surgery and the incidence of late AMD. The possible reasons for the inconsistent findings could be differences in comorbidity distributions between clinic-based patients and population-based controls [ 7 , 16 ]. Of note, the proportion of clinic-based patients with systemic comorbidities was higher than that of the healthy general population living in the community [ 40 , 41 ].…”

“…Clarifying whether there are different risks between types of AMD after cataract surgery is very important from an informed consent perspective. However, the potential for cataract surgery to increase the risk of developing AMD is a long-standing clinical question, [ 7 , 8 ] and the findings from epidemiological studies regarding these associations have been inconsistent [ 8 – 19 ]. Since then, several other studies investigating cataract surgery for AMD have been published [ 17 , 20 , 21 ].…”

The Impact of Cataract Surgery on AMD Development and Progression

“……”

Potential guidelines for cataract surgery and rehabilitation in visually impaired patients: Literature analysis

“…Regarding the potential for exacerbating retinal pathology following cataract surgery, it is important to note that epidemiological studies conducted prior to the introduction of anti-VEGF therapy demonstrated an increased risk of both exudative and atrophic forms of AMD, including heightened incidence and progression post-surgery (Figure 1A,B). [38][39][40][41] Currently, there is no conclusive evidence indicating that cataract surgery increases the incidence or progression of AMD, nor does it facilitate the transition from atrophic to neovascular forms of the disease. [42][43][44] The retinal condition should be carefully assessed before surgery, ensuring that the macula is stable, whether in an atrophic or exudative state, before scheduling the procedure.…”

“…Regarding the potential for exacerbating retinal pathology following cataract surgery, it is important to note that epidemiological studies conducted prior to the introduction of anti‐VEGF therapy demonstrated an increased risk of both exudative and atrophic forms of AMD, including heightened incidence and progression post‐surgery (Figure 1A,B ). 38 , 39 , 40 , 41 …”