Is the electrochemical or the “green chemistry” method the optimal method for the synthesis of ZnO nanoparticles for applications to biological material? Characterization and SERS on ZnO

Spectroscopic characterization and in vitro studies of biological activity of bradykinin derivatives

“…In SERS, the energy of the incident radiation is very low and the risk of sample destruction or damage is low, so it can be successfully used to study biological material. SERS uses nanostructures of Ag 24 , Au 25 , and, less commonly, Cu 26 , or other metals 27 , 28 . Metal sols are the most biologically important nanostructures because they ensure low dispersion of nanoparticle diameter in the sol, do not require strict topological control, and provide strong enhancement that decreases dramatically with a continuous metal layer 29 .…”

Electrochemistry at Krakowian research institutions

“…The scientists at the department focus on synthesis of nanomaterials [135][136][137] and electrochemical behavior of metals [138,139] and semiconductors [140,141] in aqueous and organic electrolyte solutions. The research group also works on modern directions such as green chemistry and biomaterials [142,143]. The team has collaborated with the group from, inter alia, France [144][145][146], Germany [147], UK [148], Austria [149], and Spain [150].…”

Application of Alanine Scanning to Determination of Amino Acids Essential for Peptide Adsorption at the Solid/Solution Interface and Binding to the Receptor: Surface-Enhanced Raman/Infrared Spectroscopy versus Bioactivity Assays

“…The peptides [Ala 1 ]BN 6−14 , [Ala 3 ]BN 6−14 , and [Ala 7 ]BN 6−14 behave like a native fragment of BN ([Ala 4 ]BN 6−14 ), which means that the modification at positions 1, 3, and 7 does not affect the conformational change. The biological studies reported in the literature also indicate that the active conformation of BN when interacting with GPCRs is a turn structure at positions 10−13 and hydrogen bonds between the amide NH 2 of L-methionine at position 14 of the amino acid sequence (Met 14 ) of BN and CO of Trp 8 , CO of Leu ■ EXPERIMENTAL SECTION Peptides. Peptides were synthesized via the solid-phase method using the Fmoc/tBu strategy, as previously described 74 with minor modifications.…”

“…For SERS studies, noble metals (Ag, , Au, , and less frequently Cu, , or other metals − ) are mainly used in the form of nanostructures or thin films. The SEIRA effect is mainly studied on chemical- and vapor-deposited island layers, nanoparticle-decorated layers, and periodic array-based substrates of Ag and Au. , Metal layers consist of growing and converging isolated particles that ultimately form a continuous layer.…”