1994
DOI: 10.1590/s0036-46651994000200003 View full text |Buy / Rent full text
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Abstract: Leptospirosis is an important cause of acute renal failure in our environment. Although several mechanisms are implicated, the role of rhabdomyolysis in the pathogenesis of acute renal failure in leptospirosis has not been analysed. Sixteen patients with the diagnosis of leptospiroses consecutively admitted to the hospital were prospectively studied. The disease was characterized by sudden onset in all patients and, at admission, jaundice, conjunctival suffusion and myalgias. Mild to moderate proteinuria with … Show more

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“…The decrease in GFR may not be directly dependent on the tubular damage because the FE Na was not different between the three groups. Previous clinical studies also demonstrated that rhabdomyolysis-induced acute renal injuries did not modify sodium excretion [3638]. …”
Section: Discussionmentioning
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“…The decrease in GFR may not be directly dependent on the tubular damage because the FE Na was not different between the three groups. Previous clinical studies also demonstrated that rhabdomyolysis-induced acute renal injuries did not modify sodium excretion [3638]. …”
Section: Discussionmentioning
“…Hypokalemia and polyuria in patients with leptospirosis suggest an increase in distal potassium secretion secondary to increased distal sodium delivery 32 . Ionic hypocalcemia was also observed and could be due to rhabdomyolysis or acute pancreatitis 1,24,27,36 .…”
Section: Discussionmentioning
“…Rare complications include cerebrovascular accidents (224,346), rhabdomyolysis (133,374,537), thrombotic thrombocytopenic purpura (336), acute acalculous cholecystitis (44, 401, 600), erythema nodosum (157), aortic stenosis (91), Kawasaki syndrome (291,636), reactive arthritis (633), epididymitis (285), nerve palsy (516,578), male hypogonadism (437), and Guillain-Barré syndrome (403). Cerebral arteritis, resembling Moyamoya disease, has been reported in a series of patients from China (650).…”
Section: Other Complicationsmentioning