Is it tinidazole-induced pancreatitis?

Abstract

Tinidazole may probably cause acute pancreatitis similar to metronidazole. Physicians may occasionally encounter an individual with history of metronidazole-induced pancreatitis who requires antiprotozoal therapy. We believe it may be safer to choose a drug outside the 5-aminoimidazole group in this situation.

Drug-Induced Acute Pancreatitis in Adults: Focus on Antimicrobial and Antiviral Drugs, a Narrative Review

“…Only one case of AP has been described after the use of secnidazole and another case after tinidazole ingestion [34,35]. All other underlying diseases or medications associated with AP were ruled out; however, in both cases, the rechallenge was negative.…”

Drug-Induced Acute Pancreatitis in Adults: Focus on Antimicrobial and Antiviral Drugs, a Narrative Review

“…Only one case of AP has been described after the use of secnidazole and another case after tinidazole ingestion [34,35]. All other underlying diseases or medications associated with AP were ruled out; however, in both cases, the rechallenge was negative.…”

Potassium Metabolism and Management in Patients with CKD

“…Most drugs that increase extrarenal K excretion, with the exception of cation exchange resins, are laxatives. In addition to direct K loss, secondary aldosteronism associated with extracellular fluid loss further enhances K excretion [113].…”

Drug-Induced Acute Pancreatitis in Adults: Focus on Antimicrobial and Antiviral Drugs, a Narrative Review

“…Only one case of AP has been described after the use of secnidazole and another case after tinidazole ingestion [34,35]. All other underlying diseases or medications associated with AP were ruled out; however, in both cases, the rechallenge was negative.…”

Potassium Metabolism and Management in Patients with CKD

“…Most drugs that increase extrarenal K excretion, with the exception of cation exchange resins, are laxatives. In addition to direct K loss, secondary aldosteronism associated with extracellular fluid loss further enhances K excretion [113].…”

Drug-Induced Acute Pancreatitis in Adults: Focus on Antimicrobial and Antiviral Drugs, a Narrative Review

“…Only one case of AP has been described after the use of secnidazole and another case after tinidazole ingestion [34,35]. All other underlying diseases or medications associated with AP were ruled out; however, in both cases, the rechallenge was negative.…”

Potassium Metabolism and Management in Patients with CKD

“…Most drugs that increase extrarenal K excretion, with the exception of cation exchange resins, are laxatives. In addition to direct K loss, secondary aldosteronism associated with extracellular fluid loss further enhances K excretion [113].…”