volume 3, issue 1, P5-7 2007
DOI: 10.1177/174701610700300103
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Abstract: The novel nature of certain investigational medicinal products may indicate that someone particularly knowledgeable about the risks involved should be the 'first-in-man' subject. Such self-experimentation has a noble and ethical heritage, and whilst its practice has declined of late it is perhaps timely to reconsider this situation.

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