2020
DOI: 10.3390/cancers12092338
|View full text |Cite
|
Sign up to set email alerts
|

Abstract: For the past 100 years, oncologists have relentlessly pursued the destruction of tumor cells by surgical, chemotherapeutic or radiation oncological means. Consistent with this focus, treatment plans are typically based on key characteristics of the tumor itself such as disease site, histology and staging based on local, regional and systemic dissemination. Precision medicine is similarly built on the premise that detailed knowledge of molecular alterations of tumor cells themselves enables better and more effe… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
1

Citation Types

0
3
0

Year Published

2021
2021
2023
2023

Publication Types

Select...
3
1

Relationship

0
4

Authors

Journals

citations
Cited by 4 publications
(3 citation statements)
references
References 135 publications
(140 reference statements)
0
3
0
Order By: Relevance
“…To surmount this side effect, it needs to brace every nerve for a supreme effort. Multimodality treatments include not only therapeutic administration of radiation and pharmaceutical agents such as tissue-specific radiosensitizers and radioprotectors [ 11 , 119 121 ] but also prospective application of gene therapy (i.e., to modulate target gene splicing or aberrant splicing isoforms) [ 122 ], induction of hormesis and adaptive response [ 123 , 124 ], lifestyle intervention (including but not limited to such as dietary and nutritional interventions and administration of DR mimetic drugs) [ 114 , 125 , 126 ], psychiatric management [ 127 ], and other components such as public health issues. Among the treatments, dietary intervention as one of the adjuvant therapies is with a high acceptability and feasibility [ 128 ].…”
Section: Discussionmentioning
confidence: 99%
“…To surmount this side effect, it needs to brace every nerve for a supreme effort. Multimodality treatments include not only therapeutic administration of radiation and pharmaceutical agents such as tissue-specific radiosensitizers and radioprotectors [ 11 , 119 121 ] but also prospective application of gene therapy (i.e., to modulate target gene splicing or aberrant splicing isoforms) [ 122 ], induction of hormesis and adaptive response [ 123 , 124 ], lifestyle intervention (including but not limited to such as dietary and nutritional interventions and administration of DR mimetic drugs) [ 114 , 125 , 126 ], psychiatric management [ 127 ], and other components such as public health issues. Among the treatments, dietary intervention as one of the adjuvant therapies is with a high acceptability and feasibility [ 128 ].…”
Section: Discussionmentioning
confidence: 99%
“…The articles accepted into this series focus on liver [ 4 , 5 , 6 ], uterine [ 7 ], skin [ 8 ], breast [ 9 , 10 , 11 ], prostate [ 12 ], colon [ 13 , 14 ], pancreatic [ 15 ], and acute lymphoblastic leukemia cancers [ 16 ], with a general overview of the potential impacts of obesity-related changes in host metabolism on cancer development and/or progression [ 17 ].…”
mentioning
confidence: 99%
“…Finally, Wright and colleagues review the potential links between body mass, diet, and host metabolism to how well patients respond to anti-cancer treatment [ 17 ]. Together, these manuscripts help to us understand the complex relationship between excess body weight and cancer, and highlight idiosyncrasies in different types of cancer and model systems that may be useful in further dissecting the role of obesity and cancer incidence, progression, and/or sensitivity to treatment.…”
mentioning
confidence: 99%