volume 295, issue 6589, P7-12 1987
DOI: 10.1136/bmj.295.6589.7
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R N Clayton, J P Royston, J Chapman, M Wilson, M Obhrai, R S Sawers, S S Lynch

Abstract: AbstractThe activity of the hypothalamic gonadotrophin releasing hormone pulse generator in women with regular ovulatory and anovulatory menstrual cycles was assessed to see whether changes therein are important determinants of normal and impaired ovarian function. Endogenous gonadotrophin releasing hormone secretion was inferred by measurement of the pituitary luteinising hormone response by characterisation of pulsatile luteinising hormone release over eight hours on three occasions during the course of fol…

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