“…To determine the structural similarity of TaPIMA1 to other MATE transporters in plants, we performed phylogenetic analysis of TaPIMA1 and 24 other MATE proteins from wheat, rice, Hordeum vulgare , Triticum urartu , Setaria viridis , Brachypodium distachyon , Sorghum bicolor , Arabidopsis , Arachis hypogaea , Gossypium hirsutum , Medicago truncatula , and Vitis vinifera ( Figure 2 C, Table S1 ). These 24 known-function MATE proteins encompass all the reported functions of the MATE transporters, such as disease resistance [ 38 , 39 , 40 , 49 , 50 , 51 , 52 , 53 , 54 ], aluminum tolerance [ 41 , 42 , 55 , 56 , 57 , 58 , 59 , 60 ], iron translocation [ 56 , 61 , 62 , 63 ], anthocyanidin transport [ 47 , 64 , 65 ], and heavy metals detoxification [ 43 , 44 , 66 ]. As a result, the dendrogram showed that these 25 MATE proteins were mainly clustered into two clades.…”