Irritant contact dermatitis from Agave americana L. Incorrect use of sap as "hair restorer"

Kerner, J.

doi:10.1001/archderm.108.1.102

Cited by 6 publications

(7 citation statements)

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“…A few reports of contact dermatitis following exposure to the sap of A. americana are found in the literature [4, 5]. Whether the exposure was intentional or accidental, the complaint was an immediate burning sensation, followed by erythema and edema.…”

Section: Discussionmentioning

confidence: 99%

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Contact Dermatitis with Systemic Symptoms from <i>Agave americana</i>

Brenner

Landau

Goldberg³

1998

Dermatology

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Background: Twelve cases of contact dermatitis provoked by Agave americana are described, 10 with systemic signs and symptoms and 8 with abnormal laboratory results. Results: Patient history revealed a background of intentional exposure among soldiers seeking sick leave. Treatment with oral antihistamines and topical saline compresses resulted in subsidence of the systemic symptoms within 24 h of hospitalization and regression of cutaneous manifestations in 7–10 days. Conclusion: The importance that dermatologists be alert to the possibility of self-inflicted contact dermatitis induced by exposure to plants is stressed, especially to A. americana. Systemic signs are not rare accompanying findings with this plant.

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Section: Discussionmentioning

confidence: 99%

“…Agave americana is a member of the Amaryllidaceae family which is native to hot, dry regions and is common on the Mediterranean coasts and in Mexico and the southern USA. There are few reported cases of contact dermatitis caused by A. americana [4, 5]. We describe 12 cases of contact dermatitis induced by A. americana .…”

Section: Introductionmentioning

confidence: 99%

Contact Dermatitis with Systemic Symptoms from <i>Agave americana</i>

Brenner

Landau

Goldberg³

1998

Dermatology

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“…Wattendorff (8), Epelie et al (9), and Ishii (10) reported that raphides were found abundantly in Agave americana plants. Cases of irritant contact dermatitis caused by A. americana were reported (11–13). However, the authors could not specify the causal substance but suspected that calcium oxalate as well as saponins and other plant constituents were responsible for the dermatitis.…”

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confidence: 99%

Irritant contact dermatitis caused by needle‐like calcium oxalate crystals, raphides, in Agave tequilana among workers in tequila distilleries and agave plantations

2001

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It was found that needle-like calcium oxalate crystals, raphides, are found abundantly in all tissues of Agave tequilana plants; thus, 1 droplet (0.03 ml) of juice pressed from leaves contains 100-150 crystals, 30-500 microm in length, sharpened at both ends. In tequila distilleries, 5/6 of the workers who handle the agave stems have experienced the characteristic irritation. In contrast, only 1/3 of workers in agave plantations who harvest agave plants, complain of the irritation. It is confirmed that all the irritation suffered in both distilleries and plantations takes place at bodily locations where the plants come into contact with the worker's skin in the course of their work.

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“…Irritant contact dermatitis has often been reported following exposure to the sap of Agave americana 1‐6 . However, no cases of allergic contact dermatitis have been published.…”

Section: Discussionmentioning

confidence: 99%

“…A number of cases of irritant contact dermatitis caused by Agave americana have been reported, with various presentations, but very few of these 1‐3 have been investigated by patch testing of patient and controls.…”

mentioning

confidence: 99%